Since this is the discussion forum I will offer my personal and unscientific observations:
1) Male, 50s, got Delta as vaccines were rolling out (Spring 2020). Had a serious, but treatable, at home case. Received J&J vaccine a few months later. No known side effects to vaccine. Got Omicron in Winter 2021. Very slight case. Not treated. Test positive.
2) Female, wife of above case, 50s, same exact description as case #1 above. Test positive.
3) Male, 20s, got Delta in Summer 2020. Very slight case. Not treated. Received an RNA vaccine in Summer 2021. No known vaccine side effects. Not boosted. Got Omicron in Winter 2021 and was seriously ill for about a week. Self treated at home. Test positive.
4) Male, 50s got Delta in Summer 2020. Medium case. Received RNA vaccine in 2021. No known side effects. Close exposure to case 3 above. Booster status unknown. Either had no COVID or an asymptomatic case as a result of exposure. Test positive.
5) Female, 50s, suspected slight Delta case in Fall 2020. Received RNA vaccine in Fall 2021. Reported fatigue side effect. Not eligible for booster at onset of suspected Omicron. Was medium sick. Headache, sore throat, extreme fatigue. Recovered without treatment in a week.
6) Female, 20s, got Delta in Fall 2020. Was medium sick. Typical symptoms. Recovered without treatment. Received RNA vaccine in Winter 2020. No known side effects. Booster status unknown. Got suspected Omicron Winter 2021. Was medium sick for about a week. Recovered without treatment. Test positive for Delta event.
7) Female, 20s, in household of case 6. Also medium sick with different symptoms. Recovered without treatment. Received RNA vaccine in Fall 2020. No known side effects. Booster status unknown. Suspected Omicron case Winter 2021. Was medium sick for a few days. Recovered without treatment. Test positive.
8) Female, 80s, fully RNA vaccinated plus booster and has not contracted COVID-19 (unless was asymptomatic) despite being in two households with test confirmed cases. Has been wearing N95 masks and limits social contacts. No known side effects of vaccine.
9) Female, 80s, fully RNA vaccinated plus booster and has not contracted COVID-19 (unless was asymptomatic). Has been wearing N95 and surgical masks. Limits social contacts. No known side effects of vaccine.
10) Male, 40, school worker with extensive contact to students. Fully RNA vaccinated plus booster. No known side effects to vaccine. Has not contracted COVID-19. Wears at least an N95 mask at work. Sometimes adds a surgical mask to cover a vented N95 mask. Some social limits.
11) Female, 30s, fully RNA vaccinated plus booster. No known side effects to vaccine. Has not contracted COVID-19. Wears N95 mask. Some social limits.
12) Male, 30s, fully RNA vaccinated plus booster. Sore muscle and injection site. Has not contracted COVID-19. Wears N95 mask. Limits social contacts.
13) Female, 60s, fully RNA vaccinated plus booster. Fatigue after each initial shot pairing. Has not contracted COVID-19. Wears N95 mask. Limits social contacts.
14) Male, 60s. fully RNA vaccinated plus booster. No known side effects to vaccine. Has not contracted COVID-19. Wears N95 mask. Limits social contacts.
15) Male, 60s, suspected Delta in Spring 2020 before vaccines available. Slight case. Headache, fatigue, fever. Recovered in a week with home treatment. Fully RNA vaccinated plus booster. No known side effects. No re-occurrence of COVID-19. Many co-morbidities. Wears N95 mask. Limits social contacts.
16) Female, 70s, health care worker working hospital shifts throughout pandemic. Fully RNA vaccinated plus booster. No known side effects. Has not contracted COVID-19. Wears at least N95 mask. Limits social contacts.
17) Male, 80s, never vaccinated. Kidney disease. Hospitalized and died in Fall 2020. Mask use is unknown. Test positive.
Observation limits - Asymptomatic cases may have occurred but are unknown. All of the cases above are generally healthy but cases 13 and 14 are at much higher risk for negative COVID-19 outcome.
My analysis of the small observation group above:
1) COVID-19 vaccines are not generating a large amount of side effects in generally healthy people.
2) COVID-19 vaccines may be somewhat protective against hospitalization in known cases.
3) COVID-19 vaccines are not preventing infection.
4) Of the cases without a history of COVID-19 illness - all wear N95 masks.
5) Of the cases without a history of COVID-19 illness - all limit social contacts outside of work requirements.
