tetano
Editor, Senior Moderator
Isr Med Assoc J
. 2022 Oct;24(10):627-628.
High degree atrio-ventricular block following COVID-19 vaccination
Shaden Nashashibi[SUP] 1 [/SUP], Ofir Priesler[SUP] 2 [/SUP], Uriel Levinger[SUP] 1 [/SUP], George Habib[SUP] 3 [/SUP]
Affiliations
Abstract
The coronavirus disease 2019 (COVID-19) pandemic has resulted in more than four million deaths globally. In addition to the lower respiratory system, a wide range of major organ injuries have been reported among patients infected with COVID-19. These injuries include cardiac involvement. The spectrum of cardiac manifestations includes cardiac injury, heart failure, cardiogenic shock, acute coronary syndrome, myocarditis, tachyarrhythmias, and bradyarrhythmia [1]. Different degrees of atrioventricular blocks have been reported [2]. The pathogenesis of these complications is not fully understood. Different mechanisms are proposed, including direct myocyte injury, interstitial inflammation and fibrosis, cytokine storm, plaque destabilization, and and/or hypoxia [3]. Many countries have worked toward mass vaccination using the Pfizer BioNTech (BNT162b2) COVID-19 vaccine, including Israel. We report a case of high degree atrioventricular block (AVB) following vaccination with the COVID-19 BNT162b2 vaccine.
. 2022 Oct;24(10):627-628.
High degree atrio-ventricular block following COVID-19 vaccination
Shaden Nashashibi[SUP] 1 [/SUP], Ofir Priesler[SUP] 2 [/SUP], Uriel Levinger[SUP] 1 [/SUP], George Habib[SUP] 3 [/SUP]
Affiliations
- PMID: 36309855
Abstract
The coronavirus disease 2019 (COVID-19) pandemic has resulted in more than four million deaths globally. In addition to the lower respiratory system, a wide range of major organ injuries have been reported among patients infected with COVID-19. These injuries include cardiac involvement. The spectrum of cardiac manifestations includes cardiac injury, heart failure, cardiogenic shock, acute coronary syndrome, myocarditis, tachyarrhythmias, and bradyarrhythmia [1]. Different degrees of atrioventricular blocks have been reported [2]. The pathogenesis of these complications is not fully understood. Different mechanisms are proposed, including direct myocyte injury, interstitial inflammation and fibrosis, cytokine storm, plaque destabilization, and and/or hypoxia [3]. Many countries have worked toward mass vaccination using the Pfizer BioNTech (BNT162b2) COVID-19 vaccine, including Israel. We report a case of high degree atrioventricular block (AVB) following vaccination with the COVID-19 BNT162b2 vaccine.