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Isr Med Assoc J . Candida Bloodstream Infection, a Dire Complication in Hospitalized COVID-19 Patients: Three Cases from a Single Center in Norther

tetano

Editor, Senior Moderator
Isr Med Assoc J


. 2021 Oct;23(10):615-617.

Candida Bloodstream Infection, a Dire Complication in Hospitalized COVID-19 Patients: Three Cases from a Single Center in Northern Israel


Shay Brikman[SUP] 1 2 3 [/SUP], Guy Dori[SUP] 1 2 3 [/SUP], Carmel Kasher[SUP] 4 [/SUP], Anna Yanovskay[SUP] 4 3 [/SUP], Merav Strauss[SUP] 5 [/SUP], Raul Colodner[SUP] 5 [/SUP], Naiel Bisharat[SUP] 2 6 3 [/SUP], Bibiana Chazan[SUP] 4 3 [/SUP]



Affiliations
  • PMID: 34672440

Abstract

Background: Patients with severe coronavirus disease-2019 (COVID-19) are susceptible to superimposed infections.
Objectives: To describe COVID-19 patients who presented with complications due to Candida bloodstream co-infection (candidemia) and their outcome in a single center in northern Israel (Emek Medical Center) during the second outbreak of COVID-19 in Israel (15 June 2020 to 20 September 2020).
Methods: A retrospective study of COVID-19 patients presenting with candidemia was conducted, including clinical and laboratory data. The incidence of candidemia among hospitalized COVID-19 patients was compared to a historical cohort of non-COVID-19 controls.
Results: Three COVID-19 patients complicated with candidemia were documented. All three patients died shortly after the detection of candidemia. Three different Candida sp. were isolated from the blood cultures: C. albicans, C. parapsilosis, and C. glabrata. The incidence of candidemia among COVID-19 patients was 0.679 episodes per 1000 hospital days.
Conclusions: Our small sample suggests a much higher incidence of candidemia among COVID-19 patients compared to a historical cohort of non-COVID-19 controls. All clinicians treating COVID-19 patients in GICU should be aware of this complication.
 
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