tetano
Editor, Senior Moderator
Int J Infect Dis. 2015 Jan 19. pii: S1201-9712(15)00018-1. doi: 10.1016/j.ijid.2015.01.013. [Epub ahead of print]
Isolation and characteristic analysis of a novel strain H7N9 of avian influenza virus A from a patient with influenza-like symptoms in China.
Chen F[SUP]1[/SUP], Li J[SUP]2[/SUP], Sun B[SUP]1[/SUP], Zhang H[SUP]2[/SUP], Zhang R[SUP]1[/SUP], Yuan J[SUP]1[/SUP], Ou X[SUP]3[/SUP], Ye W[SUP]1[/SUP], Chen J[SUP]1[/SUP], Liu Y[SUP]2[/SUP], Huang Y[SUP]2[/SUP].
Author information
Abstract
A novel H7N9 virus (A/Changsha/1/2013(H7N9)) identified through influenza network laboratory routine examination was retrospectively analyzed. The gene sequences of A/Changsha/1/2013(H7N9) were highly homologous to other viruses isolated in mainland China. Mutations of Q226L and G186V were found in HA protein. Amino acid deletions were found in 218-230 of NA protein and in 69-73 of NS1 protein. All viral genes except the PB1 were essentially identical to the sequences of other Chinese A H7N9 isolates. Collectively, A/Changsha/1/2013(H7N9) is highly homologous to other H7N9 avian influenza viruses isolated in mainland China.
Copyright ? 2015. Published by Elsevier Ltd.
KEYWORDS:
H7N9; avian influenza virus; genetic analysis; influenza surveillance; mutations.
PMID: 25613667 [PubMed - as supplied by publisher] Free full text
http://www.ncbi.nlm.nih.gov/pubmed/25613667
Isolation and characteristic analysis of a novel strain H7N9 of avian influenza virus A from a patient with influenza-like symptoms in China.
Chen F[SUP]1[/SUP], Li J[SUP]2[/SUP], Sun B[SUP]1[/SUP], Zhang H[SUP]2[/SUP], Zhang R[SUP]1[/SUP], Yuan J[SUP]1[/SUP], Ou X[SUP]3[/SUP], Ye W[SUP]1[/SUP], Chen J[SUP]1[/SUP], Liu Y[SUP]2[/SUP], Huang Y[SUP]2[/SUP].
Author information
Abstract
A novel H7N9 virus (A/Changsha/1/2013(H7N9)) identified through influenza network laboratory routine examination was retrospectively analyzed. The gene sequences of A/Changsha/1/2013(H7N9) were highly homologous to other viruses isolated in mainland China. Mutations of Q226L and G186V were found in HA protein. Amino acid deletions were found in 218-230 of NA protein and in 69-73 of NS1 protein. All viral genes except the PB1 were essentially identical to the sequences of other Chinese A H7N9 isolates. Collectively, A/Changsha/1/2013(H7N9) is highly homologous to other H7N9 avian influenza viruses isolated in mainland China.
Copyright ? 2015. Published by Elsevier Ltd.
KEYWORDS:
H7N9; avian influenza virus; genetic analysis; influenza surveillance; mutations.
PMID: 25613667 [PubMed - as supplied by publisher] Free full text
http://www.ncbi.nlm.nih.gov/pubmed/25613667
Last edited by a moderator: