tetano
Editor, Senior Moderator
Influenza Other Respir Viruses. 2016 Aug 2. doi: 10.1111/irv.12420. [Epub ahead of print]
[h=1]Investigating obesity as a risk factor for influenza-like illness during the 2009 H1N1 influenza pandemic using the Health Survey for England.[/h] Murphy R[SUP]1[/SUP], Fragaszy EB[SUP]1,[/SUP][SUP]2[/SUP], Hayward AC[SUP]2[/SUP], Warren-Gash C[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Following the 2009 H1N1 influenza pandemic, obesity was shown to be associated with severe influenza outcomes. It remains unclear whether obesity was a risk factor for milder influenza-like illness (ILI).
[h=4]OBJECTIVES:[/h] To determine if obesity was associated with an increased risk of self-reported ILI during the 2009 H1N1 influenza pandemic using Health Survey for England (HSE) 2010 cross-sectional data.
[h=4]METHODS:[/h] This study used HSE data collected from English households between January and December 2010. Weight and height measurements were taken by trained fieldworkers to determine obesity. ILI was defined as a positive response to the question "Have you had a flu-like illness where you felt feverish and had a cough or sore throat?" with illness occurring between May and December 2009. Multivariable logistic regression was used to evaluate the association between obesity and ILI.
[h=4]RESULTS:[/h] The study comprised 8,407 participants (6,984 adults, 1,436 children), among whom 24.7% (95% CI:23.6%-25.9%) were classified as obese. Of obese participants, 12.8% (95% CI:11.1%-14.8%) reported ILI compared to 11.8% (95% CI:10.8%-12.8%) of non-obese participants. The adjusted OR for ILI associated with obesity was 1.16 (95% CI:0.98-1.38, p=0.093). For adults and children, the adjusted ORs were 1.16 (95% CI:0.97-1.38, p=0.101) and 1.26 (95% CI:0.72-2.21, p=0.422) respectively.
[h=4]CONCLUSION:[/h] Household survey data showed no evidence that obesity was associated with an increase in self-reported ILI during the 2009 H1N1 influenza pandemic in England. Further studies using active prospective ILI surveillance combined with laboratory reporting would reduce bias and improve accuracy of outcome measurements. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] BMI ; Health Survey for England; Obesity; influenza-like illness
PMID: 27480326 DOI: 10.1111/irv.12420
[PubMed - as supplied by publisher] Free full text
[h=1]Investigating obesity as a risk factor for influenza-like illness during the 2009 H1N1 influenza pandemic using the Health Survey for England.[/h] Murphy R[SUP]1[/SUP], Fragaszy EB[SUP]1,[/SUP][SUP]2[/SUP], Hayward AC[SUP]2[/SUP], Warren-Gash C[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Following the 2009 H1N1 influenza pandemic, obesity was shown to be associated with severe influenza outcomes. It remains unclear whether obesity was a risk factor for milder influenza-like illness (ILI).
[h=4]OBJECTIVES:[/h] To determine if obesity was associated with an increased risk of self-reported ILI during the 2009 H1N1 influenza pandemic using Health Survey for England (HSE) 2010 cross-sectional data.
[h=4]METHODS:[/h] This study used HSE data collected from English households between January and December 2010. Weight and height measurements were taken by trained fieldworkers to determine obesity. ILI was defined as a positive response to the question "Have you had a flu-like illness where you felt feverish and had a cough or sore throat?" with illness occurring between May and December 2009. Multivariable logistic regression was used to evaluate the association between obesity and ILI.
[h=4]RESULTS:[/h] The study comprised 8,407 participants (6,984 adults, 1,436 children), among whom 24.7% (95% CI:23.6%-25.9%) were classified as obese. Of obese participants, 12.8% (95% CI:11.1%-14.8%) reported ILI compared to 11.8% (95% CI:10.8%-12.8%) of non-obese participants. The adjusted OR for ILI associated with obesity was 1.16 (95% CI:0.98-1.38, p=0.093). For adults and children, the adjusted ORs were 1.16 (95% CI:0.97-1.38, p=0.101) and 1.26 (95% CI:0.72-2.21, p=0.422) respectively.
[h=4]CONCLUSION:[/h] Household survey data showed no evidence that obesity was associated with an increase in self-reported ILI during the 2009 H1N1 influenza pandemic in England. Further studies using active prospective ILI surveillance combined with laboratory reporting would reduce bias and improve accuracy of outcome measurements. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] BMI ; Health Survey for England; Obesity; influenza-like illness
PMID: 27480326 DOI: 10.1111/irv.12420
[PubMed - as supplied by publisher] Free full text