tetano
Editor, Senior Moderator
Hum Vaccin Immunother. 2015 Nov 30:0. [Epub ahead of print]
[h=1]Interventions to increase seasonal influenza vaccine coverage in healthcare workers: a systematic review and meta-regression analysis.[/h] Lytras T[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Kopsachilis F[SUP]4[/SUP], Mouratidou E[SUP]1[/SUP], Papamichail D[SUP]5[/SUP], Bonovas S[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza vaccination is recommended for healthcare workers (HCWs), but coverage is often low. We reviewed studies evaluating interventions to increase seasonal influenza vaccination coverage in HCWs, including a meta-regression analysis to quantify the effect of each component. Fourty-six eligible studies were identified. Domains conferring a high risk of bias were identified in most studies. Mandatory vaccination was the most effective intervention component (Risk Ratio of being unvaccinated [RR[SUB]unvacc[/SUB]] = 0.18, 95% CI: 0.08-0.45), followed by "soft" mandates such as declination statements (RR[SUB]unvacc[/SUB] = 0.64, 95% CI: 0.45-0.92), increased awareness (RR[SUB]unvacc[/SUB] = 0.83, 95% CI: 0.71-0.97) and increased access (RR[SUB]unvacc[/SUB] = 0.88, 95% CI: 0.78-1.00). For incentives the difference was not significant, while for education no effect was observed. Heterogeneity was substantial (τ[SUP]2[/SUP] = 0.083). These results indicate that effective alternatives to mandatory HCWs influenza vaccination do exist, and need to be further explored in future studies.
[h=4]KEYWORDS:[/h] Influenza; epidemiology; healthcare; healthcare workers; influenza vaccine; meta-analysis; meta-regression; systematic review; vaccination; vaccine coverage
PMID: 26619125 [PubMed - as supplied by publisher]
[h=1]Interventions to increase seasonal influenza vaccine coverage in healthcare workers: a systematic review and meta-regression analysis.[/h] Lytras T[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Kopsachilis F[SUP]4[/SUP], Mouratidou E[SUP]1[/SUP], Papamichail D[SUP]5[/SUP], Bonovas S[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza vaccination is recommended for healthcare workers (HCWs), but coverage is often low. We reviewed studies evaluating interventions to increase seasonal influenza vaccination coverage in HCWs, including a meta-regression analysis to quantify the effect of each component. Fourty-six eligible studies were identified. Domains conferring a high risk of bias were identified in most studies. Mandatory vaccination was the most effective intervention component (Risk Ratio of being unvaccinated [RR[SUB]unvacc[/SUB]] = 0.18, 95% CI: 0.08-0.45), followed by "soft" mandates such as declination statements (RR[SUB]unvacc[/SUB] = 0.64, 95% CI: 0.45-0.92), increased awareness (RR[SUB]unvacc[/SUB] = 0.83, 95% CI: 0.71-0.97) and increased access (RR[SUB]unvacc[/SUB] = 0.88, 95% CI: 0.78-1.00). For incentives the difference was not significant, while for education no effect was observed. Heterogeneity was substantial (τ[SUP]2[/SUP] = 0.083). These results indicate that effective alternatives to mandatory HCWs influenza vaccination do exist, and need to be further explored in future studies.
[h=4]KEYWORDS:[/h] Influenza; epidemiology; healthcare; healthcare workers; influenza vaccine; meta-analysis; meta-regression; systematic review; vaccination; vaccine coverage
PMID: 26619125 [PubMed - as supplied by publisher]