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Intern Med . New-onset Systemic Lupus Erythematosus Manifestation Following COVID-19: A Case Report and Literature Review

tetano

Editor, Senior Moderator
Intern Med


. 2024 Feb 19.
doi: 10.2169/internalmedicine.3211-23. Online ahead of print. New-onset Systemic Lupus Erythematosus Manifestation Following COVID-19: A Case Report and Literature Review

Yuya Sumichika[SUP] 1 [/SUP], Jumpei Temmoku[SUP] 1 [/SUP], Kenji Saito[SUP] 1 [/SUP], Shuhei Yoshida[SUP] 1 [/SUP], Haruki Matsumoto[SUP] 1 [/SUP], Guy Watanabe[SUP] 2 [/SUP], Akihito Utsumi[SUP] 3 [/SUP], Yuya Fujita[SUP] 1 [/SUP], Naoki Matsuoka[SUP] 1 [/SUP], Tomoyuki Asano[SUP] 1 [/SUP], Shuzo Sato[SUP] 1 [/SUP], Kiyoshi Migita[SUP] 1 [/SUP]



Affiliations
Abstract

Coronavirus disease 2019 (COVID-19) is a respiratory viral disease, and several cases of autoimmune diseases have been reported after infection. This report presents the case of a 38-year-old Japanese woman who developed systemic lupus erythematosus (SLE) following COVID-19. Clinical manifestations included dermatological complications, joint pain, and positive autoantibodies. The patient met the SLE classification criteria, and renal involvement was observed. Her symptoms improved with immunosuppressive therapy. A literature review identified 10 similar cases, those with lymphopenia and renal involvement. SLE should be considered in patients with persistent nonspecific symptoms after COVID-19 infection, particularly when hematologic and renal involvement are present.

Keywords: autoimmune disease; case report; coronavirus disease 2019; literature review; systemic lupus erythematosus.

 
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