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Intern Med J . Burden of primary influenza and respiratory syncytial virus pneumonia in hospitalized adults: insights from a two-year multi-centre

tetano

Editor, Senior Moderator
Intern Med J


. 2021 Oct 11.
doi: 10.1111/imj.15583. Online ahead of print.
Burden of primary influenza and respiratory syncytial virus pneumonia in hospitalized adults: insights from a two-year multi-centre cohort study (2017-2018)


Matteo Boattini[SUP] 1 [/SUP], Lorena Charrier[SUP] 2 [/SUP], André Almeida[SUP] 3 4 [/SUP], Eirini Christaki[SUP] 5 6 [/SUP], Torcato Moreira Marques[SUP] 3 [/SUP], Valentina Tosatto[SUP] 3 4 [/SUP], Gabriele Bianco[SUP] 1 [/SUP], Marco Iannaccone[SUP] 1 [/SUP], Georgios Tsiolakkis[SUP] 6 [/SUP], Christos Karagiannis[SUP] 7 [/SUP], Panagiota Maikanti[SUP] 7 [/SUP], Lourenço Cruz[SUP] 3 [/SUP], Diogo Antão[SUP] 3 [/SUP], Maria Inês Moreira[SUP] 3 [/SUP], Rossana Cavallo[SUP] 1 [/SUP], Cristina Costa[SUP] 1 [/SUP]



Affiliations

Abstract

This two-year (2017-2018) multi-centre study on 356 adults hospitalized for influenza A/B and RSV pneumonia analysed factors associated with non-invasive ventilation (NIV) failure and in-hospital death (IHD.) Patients with both obstructive sleep apnoea or obesity hypoventilation syndrome and influenza-A virus pneumonia showed a higher risk for NIV failure (OR 4.66; 95% CI 1.42-15.30). Patients submitted to NIV showed a higher risk for IHD, regardless of comorbidities (influenza-A OR 3.00; 95% CI 1.35-6.65, influenza-B OR 4.52; 95% CI 1.13-18.01, RSV OR 5.61; 95% CI 1.26-24.93). The increased knowledge of influenza-A/B and RSV pneumonia burden may contribute to a better management of patients with viral pneumonia. This article is protected by copyright. All rights reserved.
 
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