tetano
Editor, Senior Moderator
Intern Med
. 2022 Sep 6.
doi: 10.2169/internalmedicine.9726-22. Online ahead of print.
An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection
Ryoji Goto[SUP] 1 2 [/SUP], Haruka Kawakami[SUP] 1 [/SUP], Yurino Horiuchi[SUP] 1 [/SUP], Ayaka Chikada[SUP] 1 [/SUP], Tsutomu Yasuda[SUP] 1 [/SUP], Tetsuya Suzuki[SUP] 3 [/SUP], Yusuke Miyazato[SUP] 3 [/SUP], Masahiro Ishikane[SUP] 3 [/SUP], Yuya Kishino[SUP] 4 5 [/SUP], Hideki Miyazaki[SUP] 4 [/SUP], Toru Igari[SUP] 4 [/SUP], Harutaka Katano[SUP] 6 [/SUP], Tadaki Suzuki[SUP] 6 [/SUP], Shigeo Murayama[SUP] 7 8 [/SUP], Noritoshi Arai[SUP] 1 [/SUP]
Affiliations
Abstract
We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan.
Keywords: coronavirus disease 2019 (COVID-19); infarction; neuroinfectious disease; stroke; thrombus.
. 2022 Sep 6.
doi: 10.2169/internalmedicine.9726-22. Online ahead of print.
An Autopsy Report of a Case with Cerebral Infarction Complicated by Coronavirus Disease 2019 Infection
Ryoji Goto[SUP] 1 2 [/SUP], Haruka Kawakami[SUP] 1 [/SUP], Yurino Horiuchi[SUP] 1 [/SUP], Ayaka Chikada[SUP] 1 [/SUP], Tsutomu Yasuda[SUP] 1 [/SUP], Tetsuya Suzuki[SUP] 3 [/SUP], Yusuke Miyazato[SUP] 3 [/SUP], Masahiro Ishikane[SUP] 3 [/SUP], Yuya Kishino[SUP] 4 5 [/SUP], Hideki Miyazaki[SUP] 4 [/SUP], Toru Igari[SUP] 4 [/SUP], Harutaka Katano[SUP] 6 [/SUP], Tadaki Suzuki[SUP] 6 [/SUP], Shigeo Murayama[SUP] 7 8 [/SUP], Noritoshi Arai[SUP] 1 [/SUP]
Affiliations
- PMID: 36070957
- DOI: 10.2169/internalmedicine.9726-22
Abstract
We herein report a case of cerebral infarct in a patient with coronavirus disease 2019 (COVID-19) infection who died of aspiration pneumonia. The postmortem examination of the brain revealed embolic infarct with negative findings on quantitative reverse transcription polymerase chain reaction (qRT-PCR) as well as immunohistochemistry to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The systemic examination only revealed low copy numbers of SARS-CoV-2 in the bronchus. This is the first and so far only autopsy case of COVID-19 infection with pathologic and virologic findings of the postmortem brain in Japan.
Keywords: coronavirus disease 2019 (COVID-19); infarction; neuroinfectious disease; stroke; thrombus.