tetano
Editor, Senior Moderator
Intern Med
. 2022 Jan 13.
doi: 10.2169/internalmedicine.8855-21. Online ahead of print.
Acute Lymphocyte Myocarditis Associated with Influenza Vaccination
Ryo Nakamura[SUP] 1 [/SUP], Shin-Ichi Ando[SUP] 1 2 [/SUP], Seiya Kato[SUP] 3 [/SUP], Toshiaki Kadokami[SUP] 1 [/SUP]
Affiliations
Abstract
An elderly patient was admitted to our hospital for acute heart failure soon after receiving influenza vaccination. On admission, chest radiography revealed pulmonary edema. An electrocardiogram showed poor R progression, and echocardiography showed diffuse hypokinesis and myocardial edema. The serum troponin level was elevated. A histopathological evaluation indicated active myocarditis with lymphocyte-predominant infiltrates. A drug-induced lymphocyte stimulation test (DLST) was positive. The patient rapidly recovered from heart failure after treatment with conventional heart failure drugs, such as intravenous diuretics and vasodilators. These experimental data and the clinical course suggest that influenza vaccination was responsible for heart failure due to acute lymphocyte myocarditis.
Keywords: acute lymphocyte myocarditis; heart failure; influenza vaccination.
. 2022 Jan 13.
doi: 10.2169/internalmedicine.8855-21. Online ahead of print.
Acute Lymphocyte Myocarditis Associated with Influenza Vaccination
Ryo Nakamura[SUP] 1 [/SUP], Shin-Ichi Ando[SUP] 1 2 [/SUP], Seiya Kato[SUP] 3 [/SUP], Toshiaki Kadokami[SUP] 1 [/SUP]
Affiliations
- PMID: 35022355
- DOI: 10.2169/internalmedicine.8855-21
Abstract
An elderly patient was admitted to our hospital for acute heart failure soon after receiving influenza vaccination. On admission, chest radiography revealed pulmonary edema. An electrocardiogram showed poor R progression, and echocardiography showed diffuse hypokinesis and myocardial edema. The serum troponin level was elevated. A histopathological evaluation indicated active myocarditis with lymphocyte-predominant infiltrates. A drug-induced lymphocyte stimulation test (DLST) was positive. The patient rapidly recovered from heart failure after treatment with conventional heart failure drugs, such as intravenous diuretics and vasodilators. These experimental data and the clinical course suggest that influenza vaccination was responsible for heart failure due to acute lymphocyte myocarditis.
Keywords: acute lymphocyte myocarditis; heart failure; influenza vaccination.