tetano
Editor, Senior Moderator
Acta Virol. 2014;58(4):356-358.
[h=1]Interleukin 8 enhances the immune response of ducks to avian influenza vaccine.[/h] Ruan Y, Ji X, Wen M, Zhu X, Fu X.
[h=3]Abstract[/h] Interleukins are reported to be valuable immunostimulants in enhancing the immune efficiency of conventional vaccines. In this study, the effect of expression of interleukin 8 (IL-8) on the immune response of ducks to avian influenza vaccine was investigated. The results showed that the serum antibody titer, lymphocyte transformation efficiency and serum interferon gamma (IFN-γ) level of ducks injected with avian influenza vaccine along with a plasmid expressing duck IL-8 were higher than those of ducks injected with conventional immunostimulant Astragalus polysaccharide (APS) or empty plasmid. Therefore, the duck IL-8 may be used as a good immunostimulant to enhance the immune efficiency of avian influenza vaccine in ducks. Keywords: interleukin 8; avian influenza virus; vaccine; Astragalus polasaccharide; duck; immune response.
PMID: 25518717 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25518717
[h=1]Interleukin 8 enhances the immune response of ducks to avian influenza vaccine.[/h] Ruan Y, Ji X, Wen M, Zhu X, Fu X.
[h=3]Abstract[/h] Interleukins are reported to be valuable immunostimulants in enhancing the immune efficiency of conventional vaccines. In this study, the effect of expression of interleukin 8 (IL-8) on the immune response of ducks to avian influenza vaccine was investigated. The results showed that the serum antibody titer, lymphocyte transformation efficiency and serum interferon gamma (IFN-γ) level of ducks injected with avian influenza vaccine along with a plasmid expressing duck IL-8 were higher than those of ducks injected with conventional immunostimulant Astragalus polysaccharide (APS) or empty plasmid. Therefore, the duck IL-8 may be used as a good immunostimulant to enhance the immune efficiency of avian influenza vaccine in ducks. Keywords: interleukin 8; avian influenza virus; vaccine; Astragalus polasaccharide; duck; immune response.
PMID: 25518717 [PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25518717