Intensive Hog Farms & Humans Vitamin D Deficient

[AlaskaDenise]

.........Can any studies be found that measure serum vitamin D found in intensive pig operations versus recommendations in new research regarding vitamin D.

Tom

A quick answer might be found by comparing serum vitamin D levels of swine raised entirely outdoors with those raised entirely indoors.

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[AlaskaDenise]

Re: Intensive Hog Farms & Humans Vitamin D Deficient

There are articles about Vitamin D toxicity in swine. It seems to be a commercial-feed related problem.

See: http://www.find-health-articles.com/rec_pub_1759263-clinical-findings-vitamin-d-poisoning-swine.htm

Following the links takes you to articles about human Vitamin D toxicity also. The ones I read trace it back to mistakes in milk fortification, e.g., what was labeled Vitamin D2 was actually D3. There are many good Vitamin D articles in the links.

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[AlaskaDenise]

Re: Intensive Hog Farms & Humans Vitamin D Deficient

After more thought, I believe the "mixing vessel" situation relates more to inherent RBD receptors and possibly less to a nutritional deficiency. While Vitamin D may reduce the number of influenza cases in swine, they still have a effective supply of both receptors, just as other known "mixing vessel" animals, e.g., quail.

Of course, someone could test quail and see if there are differing infection rates based on sunshine exposure. I believe the H5N1 caused a large quail die-off in ?2006? in SE Asia (?Indonesia), that was a large outdoor flock.

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[AlaskaDenise]

Re: Intensive Hog Farms & Humans Vitamin D Deficient

(This is a response to a post I may have mistakenly wiped out, sorry)

.......... but pigs are slaughtered prior to vitamin D deficient disorders to kick in.

However, they live long enough to be fantastic mixing vessels of influenza, just as humans have also become good mixing vessels.

Are you implying they are slaughtered before Vit D deficiency can be detected?

I thought that was the point of your initial question, i.e., if swine deficiency can be elimininated they may loose or reduce, the "mixing vessel" capability with the obvious outcome.


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[AlaskaDenise]

Re: Intensive Hog Farms & Humans Vitamin D Deficient

I found a wealth of relevent articles when I looked for swine VDR articles.

I googled "swine vitamin D receptors -flu". Including flu allowed too many pandemic articles and not enough swine health articles.

One example:

Effects of growth hormone administration on vitamin D metabolism and vitamin D receptors in the pig.

Author: Goff, J P : Caperna, T J : Steele, N C
Citation: Domest-Anim-Endocrinol. 1990 Jul; 7(3): 425-33

Abstract: Twelve 36-kg pigs were given either 100 micrograms/kg porcine pituitary growth hormone (pGH) or placebo injections daily for 33 days. Serum was obtained weekly for analysis of minerals and vitamin D metabolites. On day 34, the pigs were sacrificed and renal and duodenal tissue were obtained for analysis of vitamin D receptor content (VDR). Animals treated with pGH grew faster and had a higher rate of bone accretion than did control animals.

Serum concentrations of 1,25-dihydroxyvitamin D (1,25-(OH)2D) were significantly higher in pGH-treated pigs than in control pigs at all time points following initiation of treatment, with the greatest difference observed at day 28 (42.4 +/- 4.9 pg/ml in controls vs. 65.4 +/- 4.7 pg/ml in pGH-treated pigs). Serum 24,25-dihydroxy-vitamin D tended to be lower in pGH-treated pigs than in control pigs, being significantly lower on day 21 of the experiment (3.22 +/- .52 vs. 6.73 +/- 1.22 ng/ml, respectively). Serum concentrations of 25-hydroxyvitamin D and calcium were unaffected by pGH treatment. Kidneys of control pigs contained significantly more unoccupied vitamin D receptors than did kidneys from pGH-treated pigs (73.3 +/- 4.3 vs. 58.3 +/- 4.1 fmoles/mg protein). Duodenal tissue unoccupied vitamin D receptor content was similar in both pGH-treated (245 +/- 17.9 fmoles/mg protein) and control (263 +/- 21.8 fmoles/mg protein) pigs. Duodenal occupied vitamin D receptor concentration was similar in both pGH-treated (6.8 +/- .75 fmoles/mg protein) and control pigs (5.32 +/- .77 fmoles/mg protein).(ABSTRACT TRUNCATED AT 250 WORDS)

Review References: None
Notes: None
Language: English
Publication Type: Journal-Article
Keywords: Receptors, Steroid analysis : Somatotropin pharmacology : Swine metabolism : Vitamin D metabolism
URL: http://www.elsevier.com/locate/domaniend

http://grande.nal.usda.gov/ibids/index.php?mode2=detail&origin=ibids_references&therow=270920