tetano
Editor, Senior Moderator
Int Ophthalmol
. 2021 Nov 11.
doi: 10.1007/s10792-021-01938-3. Online ahead of print.
Detection of COVID-19 in tears of ICU-admitted patients with SARS-CoV-2 infection
Seyed Hashem Daryabari[SUP] 1 [/SUP], Atieh Asadollah[SUP] 2 [/SUP], Farhad Adhami Moghadam[SUP] 2 [/SUP], Ruhollah Dorostkar[SUP] 2 [/SUP], Ali Bahramifar[SUP] 2 [/SUP], Hossein Aghamollaei[SUP] 2 [/SUP]
Affiliations
Abstract
Purpose: Upon the outbreak of 2019, novel coronavirus (COVID-19) pandemic confirmed the cases surpassed 20 million. Despite a few reports identified the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with ocular manifestations, it may assess the ocular symptoms of patients with the COVID-19 by ophthalmologists facilitate the diagnosis and prevent transmission.
Methods: A total of 60 patients with the COVID-19 admitted to Baghiatallah hospital from March 2020 to May 2020 were retrospectively reviewed and analyzed for the ocular manifestations, blood tests, and reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV-2 using nasopharyngeal and conjunctival swabs.
Results: Among 60 included patients with clinically confirmed COVID-19, the median age 58.36 years (IQR: 30-88 years), 27 (45%) were male. Furthermore, 29 (48%) and 5 (8%) patients yielded positive for SARS-CoV-2 on RT-PCR from nasopharyngeal swabs and conjunctival specimens, respectively. Among 60 patients, 10 (16%) and 3 (5%), respectively, had the ocular manifestations and positive results for SARS-CoV-2 on RT-PCR from conjunctival and nasopharyngeal swabs.
Conclusion: Although the positive rate of tear RT-PCR rate is not noticeable as nasopharyngeal swabs yet, COVID-19 transmission through the eyes is biologically plausible.
Keywords: COVID-19; Nasopharyngeal RT-PCR; Ocular manifestation; Tear RT-PCR.
. 2021 Nov 11.
doi: 10.1007/s10792-021-01938-3. Online ahead of print.
Detection of COVID-19 in tears of ICU-admitted patients with SARS-CoV-2 infection
Seyed Hashem Daryabari[SUP] 1 [/SUP], Atieh Asadollah[SUP] 2 [/SUP], Farhad Adhami Moghadam[SUP] 2 [/SUP], Ruhollah Dorostkar[SUP] 2 [/SUP], Ali Bahramifar[SUP] 2 [/SUP], Hossein Aghamollaei[SUP] 2 [/SUP]
Affiliations
- PMID: 34762278
- DOI: 10.1007/s10792-021-01938-3
Abstract
Purpose: Upon the outbreak of 2019, novel coronavirus (COVID-19) pandemic confirmed the cases surpassed 20 million. Despite a few reports identified the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with ocular manifestations, it may assess the ocular symptoms of patients with the COVID-19 by ophthalmologists facilitate the diagnosis and prevent transmission.
Methods: A total of 60 patients with the COVID-19 admitted to Baghiatallah hospital from March 2020 to May 2020 were retrospectively reviewed and analyzed for the ocular manifestations, blood tests, and reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV-2 using nasopharyngeal and conjunctival swabs.
Results: Among 60 included patients with clinically confirmed COVID-19, the median age 58.36 years (IQR: 30-88 years), 27 (45%) were male. Furthermore, 29 (48%) and 5 (8%) patients yielded positive for SARS-CoV-2 on RT-PCR from nasopharyngeal swabs and conjunctival specimens, respectively. Among 60 patients, 10 (16%) and 3 (5%), respectively, had the ocular manifestations and positive results for SARS-CoV-2 on RT-PCR from conjunctival and nasopharyngeal swabs.
Conclusion: Although the positive rate of tear RT-PCR rate is not noticeable as nasopharyngeal swabs yet, COVID-19 transmission through the eyes is biologically plausible.
Keywords: COVID-19; Nasopharyngeal RT-PCR; Ocular manifestation; Tear RT-PCR.