tetano
Editor, Senior Moderator
Int J Obes (Lond)
. 2020 Nov 21.
doi: 10.1038/s41366-020-00721-1. Online ahead of print.
The association between body mass index class and coronavirus disease 2019 outcomes
Abdallah Al-Salameh[SUP] 1 2 [/SUP], Jean-Philippe Lanoix[SUP] 3 [/SUP], Youssef Bennis[SUP] 4 [/SUP], Claire Andrejak[SUP] 5 [/SUP], Etienne Brochot[SUP] 6 [/SUP], Guillaume Deschasse[SUP] 7 [/SUP], Herv? Dupont[SUP] 8 [/SUP], Vincent Goeb[SUP] 9 [/SUP], Mait? Jaureguy[SUP] 10 [/SUP], Sylvie Lion[SUP] 11 [/SUP], Julien Maizel[SUP] 12 [/SUP], Julien Moyet[SUP] 7 [/SUP], Benoit Vaysse[SUP] 13 [/SUP], Rachel Desailloud[SUP] 14 15 [/SUP], Olivier Ganry[SUP] 16 [/SUP], Jean-Luc Schmit[SUP] 3 [/SUP], Jean-Daniel Lalau[SUP] 14 15 [/SUP]
Affiliations
Abstract
Background/objectives: A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study's primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19.
Subjects/methods: Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis.
Results: In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77-3.24] and 2.58 [1.28-5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29-8.06]) and obesity (3.05 [1.25-7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment.
Conclusions: Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death.
. 2020 Nov 21.
doi: 10.1038/s41366-020-00721-1. Online ahead of print.
The association between body mass index class and coronavirus disease 2019 outcomes
Abdallah Al-Salameh[SUP] 1 2 [/SUP], Jean-Philippe Lanoix[SUP] 3 [/SUP], Youssef Bennis[SUP] 4 [/SUP], Claire Andrejak[SUP] 5 [/SUP], Etienne Brochot[SUP] 6 [/SUP], Guillaume Deschasse[SUP] 7 [/SUP], Herv? Dupont[SUP] 8 [/SUP], Vincent Goeb[SUP] 9 [/SUP], Mait? Jaureguy[SUP] 10 [/SUP], Sylvie Lion[SUP] 11 [/SUP], Julien Maizel[SUP] 12 [/SUP], Julien Moyet[SUP] 7 [/SUP], Benoit Vaysse[SUP] 13 [/SUP], Rachel Desailloud[SUP] 14 15 [/SUP], Olivier Ganry[SUP] 16 [/SUP], Jean-Luc Schmit[SUP] 3 [/SUP], Jean-Daniel Lalau[SUP] 14 15 [/SUP]
Affiliations
- PMID: 33221825
- DOI: 10.1038/s41366-020-00721-1
Abstract
Background/objectives: A growing body of data suggests that obesity influences coronavirus disease 2019 (COVID-19). Our study's primary objective was to assess the association between body mass index (BMI) categories and critical forms of COVID-19.
Subjects/methods: Data on consecutive adult patients hospitalized with laboratory-confirmed COVID-19 at Amiens University Hospital (Amiens, France) were extracted retrospectively. The association between BMI categories and the composite primary endpoint (admission to the intensive care unit or death) was probed in a logistic regression analysis.
Results: In total, 433 patients were included, and BMI data were available for 329: 20 were underweight (6.1%), 95 have a normal weight (28.9%), 90 were overweight (27.4%), and 124 were obese (37.7%). The BMI category was associated with the primary endpoint in the fully adjusted model; the odds ratio (OR) [95% confidence interval (CI)] for overweight and obesity were respectively 1.58 [0.77-3.24] and 2.58 [1.28-5.31]. The ORs [95% CI] for ICU admission were similar for overweight (3.16 [1.29-8.06]) and obesity (3.05 [1.25-7.82]) in the fully adjusted model. The unadjusted ORs for death were similar in all BMI categories while obesity only was associated with higher risk after adjustment.
Conclusions: Our results suggest that overweight (and not only obesity) is associated with ICU admission, but overweight is not associated with death.