tetano
Editor, Senior Moderator
Int J Med Sci
. 2020 Sep 21;17(17):2644-2652.
doi: 10.7150/ijms.48696. eCollection 2020.
Clinical characteristics and longitudinal chest CT features of healthcare workers hospitalized with coronavirus disease 2019 (COVID-19)
Huaping Liu[SUP] 1 [/SUP], Shiyong Luo[SUP] 2 [/SUP], Hailan Li[SUP] 3 [/SUP], Youming Zhang[SUP] 4 [/SUP], Chiyao Huang[SUP] 5 [/SUP], Xili Li[SUP] 2 [/SUP], Yiqing Tan[SUP] 2 [/SUP], Mingna Chen[SUP] 6 [/SUP]
Affiliations
Abstract
Rationale: The clinical data and corresponding dynamic CT findings were investigated in detail to describe the clinical and imaging profiles of COVID-19 pneumonia disease progression. Methods: Forty HCWs with COVID-19 were included in this study and 30 enrolled for imaging assessment. Disease was divided into four stages based on time from onset: stage 1 (1-6 days), stage 2 (7-13 days), stage 3 (14-22 days), and stage 4 (> 22 days). Clinical wand imaging data were analyzed retrospectively. Results: The cohort included 33 female and 7 male cases, with a median age of 40 years. Six had underlying comorbidities. More than half of the cases were nurses (22, 55%). Each stage included 39, 37, 34 and 32 CTs, respectively. Bilateral lesions, multifocal lesions and lesions with GGO pattern occurred in both lower lobes at all stages. The crazy-paving pattern (20, 54%), air bronchogram (13, 35%), and pleural effusion (2, 5%) were the most common CT features in stage 2. Consolidation score peaked in stage 2 whereas total lesions score peaked in stage 3. Conclusions: COVID-19 pneumonia in HCWs has a potential predilection for younger female workers. Stage 2 of COVID-19 pneumonia may be the key period for controlling progression of the disease, and consolidation scores may be an objective reflection of the severity of lung involvement.
Keywords: COVID-19; CT; SARS-CoV-2; healthcare workers.
. 2020 Sep 21;17(17):2644-2652.
doi: 10.7150/ijms.48696. eCollection 2020.
Clinical characteristics and longitudinal chest CT features of healthcare workers hospitalized with coronavirus disease 2019 (COVID-19)
Huaping Liu[SUP] 1 [/SUP], Shiyong Luo[SUP] 2 [/SUP], Hailan Li[SUP] 3 [/SUP], Youming Zhang[SUP] 4 [/SUP], Chiyao Huang[SUP] 5 [/SUP], Xili Li[SUP] 2 [/SUP], Yiqing Tan[SUP] 2 [/SUP], Mingna Chen[SUP] 6 [/SUP]
Affiliations
- PMID: 33162792
- PMCID: PMC7645347
- DOI: 10.7150/ijms.48696
Abstract
Rationale: The clinical data and corresponding dynamic CT findings were investigated in detail to describe the clinical and imaging profiles of COVID-19 pneumonia disease progression. Methods: Forty HCWs with COVID-19 were included in this study and 30 enrolled for imaging assessment. Disease was divided into four stages based on time from onset: stage 1 (1-6 days), stage 2 (7-13 days), stage 3 (14-22 days), and stage 4 (> 22 days). Clinical wand imaging data were analyzed retrospectively. Results: The cohort included 33 female and 7 male cases, with a median age of 40 years. Six had underlying comorbidities. More than half of the cases were nurses (22, 55%). Each stage included 39, 37, 34 and 32 CTs, respectively. Bilateral lesions, multifocal lesions and lesions with GGO pattern occurred in both lower lobes at all stages. The crazy-paving pattern (20, 54%), air bronchogram (13, 35%), and pleural effusion (2, 5%) were the most common CT features in stage 2. Consolidation score peaked in stage 2 whereas total lesions score peaked in stage 3. Conclusions: COVID-19 pneumonia in HCWs has a potential predilection for younger female workers. Stage 2 of COVID-19 pneumonia may be the key period for controlling progression of the disease, and consolidation scores may be an objective reflection of the severity of lung involvement.
Keywords: COVID-19; CT; SARS-CoV-2; healthcare workers.