tetano
Editor, Senior Moderator
Int J Infect Dis
. 2021 Apr 3;S1201-9712(21)00300-3.
doi: 10.1016/j.ijid.2021.03.082. Online ahead of print.
The spatiotemporal trend of renal involvement in COVID-19: a pooled analysis of 17,134 patients
Yi-Fu Feng[SUP] 1 [/SUP], Kun-Peng Wang[SUP] 1 [/SUP], Jing-Gang Mo[SUP] 1 [/SUP], Ying-He Xu[SUP] 2 [/SUP], Lie-Zhi Wang[SUP] 1 [/SUP], Chong Jin[SUP] 1 [/SUP], Xiang Chen[SUP] 3 [/SUP], Bin Yi[SUP] 4 [/SUP]
Affiliations
Abstract
Background: The spatiotemporal trend of renal involvement in Coronavirus Disease 2019(COVID-19) patients is still unclear. Therefore, we seek to reveal the dynamics of renal involvement superimposed COVID-19 according to time and space.
Methods: The COVID-19 patients reporting the renal involvement were enrolled in our study. We collected the following information: the first author, patient demographics, patients enrolled period, location, definition of acute kidney injury (AKI), prevalence of AKI and renal replacement treatment (RRT).
Results: 17,134 patients were included finally. The overall prevalence of AKI in COVID-19 patients was 19%, which 7% of them underwent RRT. And the overall risk of AKI in patients enrolled before March 1, 2020 (9%) was significantly lower than that after March 1, 2020 (36%) (P < 0.00001). Moreover, the overall risk of AKI outside Asia (35%) was significantly higher than that in Asia (10%) (P < 0.00001). Additionally, similar to patients required RRT, AKI patients would more tend to become seriously ill or even die (P < 0.00001).
Conclusions: This study firstly reports that renal involvement superimposed COVID-19, a comorbidity portending a poor prognosis, has become an increasingly serious problem over time, and more common outside Asia. Thus, more concerns should be offered to manage the specific group of patients.
Keywords: coronavirus disease 2019; renal involvement; spatiotemporal trend.
. 2021 Apr 3;S1201-9712(21)00300-3.
doi: 10.1016/j.ijid.2021.03.082. Online ahead of print.
The spatiotemporal trend of renal involvement in COVID-19: a pooled analysis of 17,134 patients
Yi-Fu Feng[SUP] 1 [/SUP], Kun-Peng Wang[SUP] 1 [/SUP], Jing-Gang Mo[SUP] 1 [/SUP], Ying-He Xu[SUP] 2 [/SUP], Lie-Zhi Wang[SUP] 1 [/SUP], Chong Jin[SUP] 1 [/SUP], Xiang Chen[SUP] 3 [/SUP], Bin Yi[SUP] 4 [/SUP]
Affiliations
- PMID: 33823283
- DOI: 10.1016/j.ijid.2021.03.082
Abstract
Background: The spatiotemporal trend of renal involvement in Coronavirus Disease 2019(COVID-19) patients is still unclear. Therefore, we seek to reveal the dynamics of renal involvement superimposed COVID-19 according to time and space.
Methods: The COVID-19 patients reporting the renal involvement were enrolled in our study. We collected the following information: the first author, patient demographics, patients enrolled period, location, definition of acute kidney injury (AKI), prevalence of AKI and renal replacement treatment (RRT).
Results: 17,134 patients were included finally. The overall prevalence of AKI in COVID-19 patients was 19%, which 7% of them underwent RRT. And the overall risk of AKI in patients enrolled before March 1, 2020 (9%) was significantly lower than that after March 1, 2020 (36%) (P < 0.00001). Moreover, the overall risk of AKI outside Asia (35%) was significantly higher than that in Asia (10%) (P < 0.00001). Additionally, similar to patients required RRT, AKI patients would more tend to become seriously ill or even die (P < 0.00001).
Conclusions: This study firstly reports that renal involvement superimposed COVID-19, a comorbidity portending a poor prognosis, has become an increasingly serious problem over time, and more common outside Asia. Thus, more concerns should be offered to manage the specific group of patients.
Keywords: coronavirus disease 2019; renal involvement; spatiotemporal trend.