tetano
Editor, Senior Moderator
Int J Infect Dis
. 2021 Apr 2;S1201-9712(21)00301-5.
doi: 10.1016/j.ijid.2021.03.083. Online ahead of print.
Simultaneously Complete but Not Partial Taste and Smell Losses were Associated with SAR-CoV-2 Infection
Dunyaporn Trachootham[SUP] 1 [/SUP], Supeda Thongyen[SUP] 2 [/SUP], Aroonwan Lam-Ubol[SUP] 3 [/SUP], Nattida Chotechuang[SUP] 4 [/SUP], Wannarat Pongpirul[SUP] 2 [/SUP], Wisit Prasithsirikul[SUP] 2 [/SUP]
Affiliations
Abstract
Objectives: To investigate the association between taste and smell losses and SAR-CoV-2 infection, and elucidate whether taste preference influences such taste loss METHODS: A matched case-control study was conducted in 366 Thais including RT-PCR confirmed SAR-CoV-2 positive (n = 122, Case) and negative (n = 244, Control) groups. Taste, smell and appetite changes were assessed by self-reported visual analog scale. Preference on sweet, salty, umami, sour, bitter and spicy were judged by the validated TASTE-26 questionnaire.
Results: Partial taste and smell losses were observed in both groups, while complete losses (ageusia and anosmia) were detected only in Case group. Moreover, only ageusia and anosmia were associated with SAR-CoV-2 positivity (p < 0.001, OR = 14.5 and 27.5, respectively). Taste, smell and appetite scores were more severely reduced in Case group (p < 0.0001). Multivariate analysis showed that anosmia and ageusia were the best predictors of SAR-CoV-2 positivity, followed by appetite loss and fever. Simultaneous losses of taste and smell but not taste preferences were associated with SAR-CoV-2 positivity (p < 0.01, OR = 2.28) CONCLUSIONS: Complete, not partial, taste and smell losses were the best predictors of SAR-CoV-2 infection. During the coronavirus COVID-19 pandemic, healthy persons with sudden simultaneously complete taste and smell losses should be screened for COVID-19.
Keywords: Appetite; COVID-19; Case-control study; Smell; Taste; Thai.
. 2021 Apr 2;S1201-9712(21)00301-5.
doi: 10.1016/j.ijid.2021.03.083. Online ahead of print.
Simultaneously Complete but Not Partial Taste and Smell Losses were Associated with SAR-CoV-2 Infection
Dunyaporn Trachootham[SUP] 1 [/SUP], Supeda Thongyen[SUP] 2 [/SUP], Aroonwan Lam-Ubol[SUP] 3 [/SUP], Nattida Chotechuang[SUP] 4 [/SUP], Wannarat Pongpirul[SUP] 2 [/SUP], Wisit Prasithsirikul[SUP] 2 [/SUP]
Affiliations
- PMID: 33819604
- DOI: 10.1016/j.ijid.2021.03.083
Abstract
Objectives: To investigate the association between taste and smell losses and SAR-CoV-2 infection, and elucidate whether taste preference influences such taste loss METHODS: A matched case-control study was conducted in 366 Thais including RT-PCR confirmed SAR-CoV-2 positive (n = 122, Case) and negative (n = 244, Control) groups. Taste, smell and appetite changes were assessed by self-reported visual analog scale. Preference on sweet, salty, umami, sour, bitter and spicy were judged by the validated TASTE-26 questionnaire.
Results: Partial taste and smell losses were observed in both groups, while complete losses (ageusia and anosmia) were detected only in Case group. Moreover, only ageusia and anosmia were associated with SAR-CoV-2 positivity (p < 0.001, OR = 14.5 and 27.5, respectively). Taste, smell and appetite scores were more severely reduced in Case group (p < 0.0001). Multivariate analysis showed that anosmia and ageusia were the best predictors of SAR-CoV-2 positivity, followed by appetite loss and fever. Simultaneous losses of taste and smell but not taste preferences were associated with SAR-CoV-2 positivity (p < 0.01, OR = 2.28) CONCLUSIONS: Complete, not partial, taste and smell losses were the best predictors of SAR-CoV-2 infection. During the coronavirus COVID-19 pandemic, healthy persons with sudden simultaneously complete taste and smell losses should be screened for COVID-19.
Keywords: Appetite; COVID-19; Case-control study; Smell; Taste; Thai.