tetano
Editor, Senior Moderator
Int J Infect Dis
. 2020 Nov 18;S1201-9712(20)32465-6.
doi: 10.1016/j.ijid.2020.11.156. Online ahead of print.
Pneumonia in medical professionals during COVID-19 outbreak in cardiovascular hospital
Ivan Ilic[SUP] 1 [/SUP], Marina Zdravkovic[SUP] 2 [/SUP], Stefan Timcic[SUP] 2 [/SUP], Dragana Unic Stojanovic[SUP] 3 [/SUP], Milovan Bojic[SUP] 4 [/SUP], Goran Loncar[SUP] 4 [/SUP]
Affiliations
Abstract
Objectives: The pandemic of coronavirus associated disease (COVID-19) placed the health care workers at high risk. We investigated clinical and treatment characteristics of infected medical professionals in a cardiovascular hospital.
Methods: The study was retrospective, conducted in tertiary cardiovascular hospital and included employees with confirmed coronavirus infection. They filled out a questionnaire about health status, symptoms, admission to hospital and treatment. The vaccination status against tuberculosis, hepatitis B and seasonal influenza was assessed. Pneumonia was defined as CT finding of ground glass opacifications (GGO) with consolidations typical for COVID-19.
Results: The study included 107 confirmed cases of COVID - 19 out of 726 employees (15%). Most of the infected were from cardiac surgery department (74/107, 69%). Substantial number of employees did not have any symptoms [31 (28.9%)] and 38 patients (35.5%) were admitted to hospital. The average hospital length of stay was 8.1 ? 5.6 days. Seventy-five of 107 (70.1%) received seasonal influenza vaccine. Pneumonia with CT features of GGO and consolidation occurred in 25/107 (23.4%) patients of which 14/107 (13.1%) had bilateral involvement. In multivariate logistic regression analysis including recognized characteristics associated with worse outcomes in COVID-19 (obesity, diabetes mellitus, coronary artery disease, cerebrovascular disease, current smoking, heart failure, influenza immunization), only influenza immunization remained an independent predictor of occurrence of bilateral pneumonia (OR 0.207; 95%CI[0.050 - 0.847]; p = 0.029).
Conclusions: The association of influenza immunization and less aggressive form of pneumonia might provide a finding that supports the institution of preventive measures that can be beneficial in reduction of global coronavirus burden.
Keywords: coronavirus; immunization; influenza; pneumonia.
. 2020 Nov 18;S1201-9712(20)32465-6.
doi: 10.1016/j.ijid.2020.11.156. Online ahead of print.
Pneumonia in medical professionals during COVID-19 outbreak in cardiovascular hospital
Ivan Ilic[SUP] 1 [/SUP], Marina Zdravkovic[SUP] 2 [/SUP], Stefan Timcic[SUP] 2 [/SUP], Dragana Unic Stojanovic[SUP] 3 [/SUP], Milovan Bojic[SUP] 4 [/SUP], Goran Loncar[SUP] 4 [/SUP]
Affiliations
- PMID: 33220441
- DOI: 10.1016/j.ijid.2020.11.156
Abstract
Objectives: The pandemic of coronavirus associated disease (COVID-19) placed the health care workers at high risk. We investigated clinical and treatment characteristics of infected medical professionals in a cardiovascular hospital.
Methods: The study was retrospective, conducted in tertiary cardiovascular hospital and included employees with confirmed coronavirus infection. They filled out a questionnaire about health status, symptoms, admission to hospital and treatment. The vaccination status against tuberculosis, hepatitis B and seasonal influenza was assessed. Pneumonia was defined as CT finding of ground glass opacifications (GGO) with consolidations typical for COVID-19.
Results: The study included 107 confirmed cases of COVID - 19 out of 726 employees (15%). Most of the infected were from cardiac surgery department (74/107, 69%). Substantial number of employees did not have any symptoms [31 (28.9%)] and 38 patients (35.5%) were admitted to hospital. The average hospital length of stay was 8.1 ? 5.6 days. Seventy-five of 107 (70.1%) received seasonal influenza vaccine. Pneumonia with CT features of GGO and consolidation occurred in 25/107 (23.4%) patients of which 14/107 (13.1%) had bilateral involvement. In multivariate logistic regression analysis including recognized characteristics associated with worse outcomes in COVID-19 (obesity, diabetes mellitus, coronary artery disease, cerebrovascular disease, current smoking, heart failure, influenza immunization), only influenza immunization remained an independent predictor of occurrence of bilateral pneumonia (OR 0.207; 95%CI[0.050 - 0.847]; p = 0.029).
Conclusions: The association of influenza immunization and less aggressive form of pneumonia might provide a finding that supports the institution of preventive measures that can be beneficial in reduction of global coronavirus burden.
Keywords: coronavirus; immunization; influenza; pneumonia.