tetano
Editor, Senior Moderator
Int J Infect Dis
. 2021 Jan 18;S1201-9712(21)00047-3.
doi: 10.1016/j.ijid.2021.01.036. Online ahead of print.
Epidemiology, characteristics, and outcomes of hospitalized children with COVID-19 in Oman: A multicenter cohort study
Laila S Al Yazidi[SUP] 1 [/SUP], Zaid Al Hinai[SUP] 2 [/SUP], Badriya Al Waili[SUP] 3 [/SUP], Hilal Al Hashami[SUP] 4 [/SUP], Mohammed Al Reesi[SUP] 5 [/SUP], Farhana Al Othmani[SUP] 6 [/SUP], Balqees Al Noobi[SUP] 7 [/SUP], Nuha Al Tahir[SUP] 8 [/SUP], Nagi Elsidig[SUP] 9 [/SUP], Lamya Al Barwani[SUP] 10 [/SUP], Ibrahim Al Busaidi[SUP] 11 [/SUP], Bushra Al Jabri[SUP] 12 [/SUP], Abdullah Al Qayoudhi[SUP] 13 [/SUP], Amal Al Maani[SUP] 14 [/SUP], Nawal Al-Maskari[SUP] 15 [/SUP]
Affiliations
Abstract
Objectives: To describe the epidemiology, clinical and laboratory features and outcome of hospitalized children with coronavirus disease 2019 (COVID-19) in a Middle Eastern setting.
Methods: We describe a multicenter retrospective study of children hospitalized with confirmed COVID-19 in 7 centres across Oman between February 2020 and July 2020.
Results: In total, 56 children < 14 years of age required hospitalization in seven Omani centres over five months (February - July 2020). Thirty-seven (68%) children were admitted with uncomplicated COVID-19, 13 (23%) with pneumonia and 5 (9%) with the multisystem inflammatory syndrome in children (MIS-C). Infants constituted (23/56,41%) and around half of them (12/23,52%) were below 2-months of age. Fever was the most common symptom (46;82%) followed by respiratory symptoms in (33; 59%) and gastrointestinal symptoms (31;55%). Twenty-two (39%) children had underlying medical conditions; sickle cell disease in (7; 13%) followed by chronic respiratory disease (4; 7%) and severe neurological impairment (4; 7%). We found that leukocytosis, elevated inflammatory markers, and anemia for age were independently associated with intensive care admission. There were no mortalities related to admission with COVID-19 in this cohort.
Conclusion: Most of the children hospitalized with confirmed COVID-19 had a mild course and a satisfactory outcome. Sickle cell disease is the commonest comorbidity associated with pediatric admission of COVID-19 in Oman.
Keywords: COVID-19; Oman; children; hospitalized; outcome.
. 2021 Jan 18;S1201-9712(21)00047-3.
doi: 10.1016/j.ijid.2021.01.036. Online ahead of print.
Epidemiology, characteristics, and outcomes of hospitalized children with COVID-19 in Oman: A multicenter cohort study
Laila S Al Yazidi[SUP] 1 [/SUP], Zaid Al Hinai[SUP] 2 [/SUP], Badriya Al Waili[SUP] 3 [/SUP], Hilal Al Hashami[SUP] 4 [/SUP], Mohammed Al Reesi[SUP] 5 [/SUP], Farhana Al Othmani[SUP] 6 [/SUP], Balqees Al Noobi[SUP] 7 [/SUP], Nuha Al Tahir[SUP] 8 [/SUP], Nagi Elsidig[SUP] 9 [/SUP], Lamya Al Barwani[SUP] 10 [/SUP], Ibrahim Al Busaidi[SUP] 11 [/SUP], Bushra Al Jabri[SUP] 12 [/SUP], Abdullah Al Qayoudhi[SUP] 13 [/SUP], Amal Al Maani[SUP] 14 [/SUP], Nawal Al-Maskari[SUP] 15 [/SUP]
Affiliations
- PMID: 33476759
- DOI: 10.1016/j.ijid.2021.01.036
Abstract
Objectives: To describe the epidemiology, clinical and laboratory features and outcome of hospitalized children with coronavirus disease 2019 (COVID-19) in a Middle Eastern setting.
Methods: We describe a multicenter retrospective study of children hospitalized with confirmed COVID-19 in 7 centres across Oman between February 2020 and July 2020.
Results: In total, 56 children < 14 years of age required hospitalization in seven Omani centres over five months (February - July 2020). Thirty-seven (68%) children were admitted with uncomplicated COVID-19, 13 (23%) with pneumonia and 5 (9%) with the multisystem inflammatory syndrome in children (MIS-C). Infants constituted (23/56,41%) and around half of them (12/23,52%) were below 2-months of age. Fever was the most common symptom (46;82%) followed by respiratory symptoms in (33; 59%) and gastrointestinal symptoms (31;55%). Twenty-two (39%) children had underlying medical conditions; sickle cell disease in (7; 13%) followed by chronic respiratory disease (4; 7%) and severe neurological impairment (4; 7%). We found that leukocytosis, elevated inflammatory markers, and anemia for age were independently associated with intensive care admission. There were no mortalities related to admission with COVID-19 in this cohort.
Conclusion: Most of the children hospitalized with confirmed COVID-19 had a mild course and a satisfactory outcome. Sickle cell disease is the commonest comorbidity associated with pediatric admission of COVID-19 in Oman.
Keywords: COVID-19; Oman; children; hospitalized; outcome.