tetano
Editor, Senior Moderator
Int J Infect Dis
. 2020 Jun 11;S1201-9712(20)30456-2.
doi: 10.1016/j.ijid.2020.06.020. Online ahead of print.
Duration of Viral Shedding in Asymptomatic or Mild Cases of Novel Coronavirus Disease 2019 (COVID-19) From a Cruise Ship: A Single-Hospital Experience in Tokyo, Japan
Yuka Miyamae[SUP] 1 [/SUP], Toshiya Hayashi[SUP] 2 [/SUP], Hitoshi Yonezawa[SUP] 2 [/SUP], Jin Fujihara[SUP] 1 [/SUP], Yousuke Matsumoto[SUP] 1 [/SUP], Takafumi Ito[SUP] 1 [/SUP], Takaya Tsubota[SUP] 1 [/SUP], Koji Ishii[SUP] 3 [/SUP]
Affiliations
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of novel coronavirus disease 2019 (COVID-19) first reported in Wuhan, China, has spread across the world, and has been characterized as a global pandemic. The propagation from asymptomatic polymerase chain reaction (PCR)-positive individuals represents a complicating factor in the efforts to control the COVID-19 pandemic. We examined the course of PCR assays and duration of viral shedding in 23 asymptomatic or mild COVID-19 patients from the cruise ship who were admitted to our hospital. Among these 23 cases, the median duration of viral shedding was 19 days (range, 6-37 days) from initial viral detection. Eight cases (35%) had another positive PCR result after testing negative once. Although the duration of viral shedding was approximately 3 weeks, the infectivity and transmissibility period from asymptomatic and mild COVID-19 cases is unclear. Further studies are needed to determine how long such asymptomatic and mild COVID-19 cases have the infectivity.
Keywords: asymptomatic; coronavirus disease 2019; polymerase chain reaction.; severe acute respiratory syndrome coronavirus 2; viral shedding.
. 2020 Jun 11;S1201-9712(20)30456-2.
doi: 10.1016/j.ijid.2020.06.020. Online ahead of print.
Duration of Viral Shedding in Asymptomatic or Mild Cases of Novel Coronavirus Disease 2019 (COVID-19) From a Cruise Ship: A Single-Hospital Experience in Tokyo, Japan
Yuka Miyamae[SUP] 1 [/SUP], Toshiya Hayashi[SUP] 2 [/SUP], Hitoshi Yonezawa[SUP] 2 [/SUP], Jin Fujihara[SUP] 1 [/SUP], Yousuke Matsumoto[SUP] 1 [/SUP], Takafumi Ito[SUP] 1 [/SUP], Takaya Tsubota[SUP] 1 [/SUP], Koji Ishii[SUP] 3 [/SUP]
Affiliations
- PMID: 32535295
- PMCID: PMC7289725
- DOI: 10.1016/j.ijid.2020.06.020
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of novel coronavirus disease 2019 (COVID-19) first reported in Wuhan, China, has spread across the world, and has been characterized as a global pandemic. The propagation from asymptomatic polymerase chain reaction (PCR)-positive individuals represents a complicating factor in the efforts to control the COVID-19 pandemic. We examined the course of PCR assays and duration of viral shedding in 23 asymptomatic or mild COVID-19 patients from the cruise ship who were admitted to our hospital. Among these 23 cases, the median duration of viral shedding was 19 days (range, 6-37 days) from initial viral detection. Eight cases (35%) had another positive PCR result after testing negative once. Although the duration of viral shedding was approximately 3 weeks, the infectivity and transmissibility period from asymptomatic and mild COVID-19 cases is unclear. Further studies are needed to determine how long such asymptomatic and mild COVID-19 cases have the infectivity.
Keywords: asymptomatic; coronavirus disease 2019; polymerase chain reaction.; severe acute respiratory syndrome coronavirus 2; viral shedding.