tetano
Editor, Senior Moderator
Int J Infect Dis
. 2021 Jun 16;S1201-9712(21)00513-0.
doi: 10.1016/j.ijid.2021.06.026. Online ahead of print.
Association of lung ultrasound score with mortality and severity of COVID-19: A Meta-analysis and Trial Sequential Analysis
Guang Song[SUP] 1 [/SUP], Wei Qiao[SUP] 2 [/SUP], Xin Wang[SUP] 3 [/SUP], Xiaona Yu[SUP] 4 [/SUP]
Affiliations
Abstract
Objectives: The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread all over the world. Lung ultrasound (LUS) has emerged as a useful tool for diagnosis of many respiratory diseases. The prognostic role of LUS in COVID-19 patients has not yet been established.
Methods: Several databases were searched on April 9, 2021. The difference of LUS score between the death and survival groups, and the relationship between LUS score and COVID-19 severity were both assessed.
Results: The LUS score was significantly higher in the death group compared to the survival group (weighted mean difference (WMD) = 8.21, 95% CI: 4.74-11.67, P < 0.001), confirm by the trial sequential analysis. Those with mild/moderate, severe, and critical COVID-19 had a progressively higher LUS score (Critical vs. severe: WMD = 8.78, 95% CI: 4.17-13.38, P < 0.001; Critical vs. mild/moderate/severe: WMD = 10.00, 95% CI: 6.83-13.17, P < 0.001; Severe vs. moderate: WMD = 5.96, 95% CI: 3.48-8.44, P < 0.001; Severe vs. mild/moderate: WMD = 7.31, 95% CI: 4.45-10.17, P < 0.001).
Conclusions: The LUS score was associated with mortality and severity of COVID-19. The LUS score might be a risk stratification tool for COVID-19 patients.
Keywords: COVID-19; Lung ultrasound score; Meta-analysis; Mortality; Severity.
. 2021 Jun 16;S1201-9712(21)00513-0.
doi: 10.1016/j.ijid.2021.06.026. Online ahead of print.
Association of lung ultrasound score with mortality and severity of COVID-19: A Meta-analysis and Trial Sequential Analysis
Guang Song[SUP] 1 [/SUP], Wei Qiao[SUP] 2 [/SUP], Xin Wang[SUP] 3 [/SUP], Xiaona Yu[SUP] 4 [/SUP]
Affiliations
- PMID: 34146693
- DOI: 10.1016/j.ijid.2021.06.026
Abstract
Objectives: The coronavirus disease 2019 (COVID-19) pandemic has rapidly spread all over the world. Lung ultrasound (LUS) has emerged as a useful tool for diagnosis of many respiratory diseases. The prognostic role of LUS in COVID-19 patients has not yet been established.
Methods: Several databases were searched on April 9, 2021. The difference of LUS score between the death and survival groups, and the relationship between LUS score and COVID-19 severity were both assessed.
Results: The LUS score was significantly higher in the death group compared to the survival group (weighted mean difference (WMD) = 8.21, 95% CI: 4.74-11.67, P < 0.001), confirm by the trial sequential analysis. Those with mild/moderate, severe, and critical COVID-19 had a progressively higher LUS score (Critical vs. severe: WMD = 8.78, 95% CI: 4.17-13.38, P < 0.001; Critical vs. mild/moderate/severe: WMD = 10.00, 95% CI: 6.83-13.17, P < 0.001; Severe vs. moderate: WMD = 5.96, 95% CI: 3.48-8.44, P < 0.001; Severe vs. mild/moderate: WMD = 7.31, 95% CI: 4.45-10.17, P < 0.001).
Conclusions: The LUS score was associated with mortality and severity of COVID-19. The LUS score might be a risk stratification tool for COVID-19 patients.
Keywords: COVID-19; Lung ultrasound score; Meta-analysis; Mortality; Severity.