tetano
Editor, Senior Moderator
Int J Infect Dis
. 2022 Aug 20;S1201-9712(22)00483-0.
doi: 10.1016/j.ijid.2022.08.013. Online ahead of print.
Acute Encephalopathy in a 6-Year-Old Child with Concurrent Coronavirus Disease-2019 Infection: A Case Report from Saudi Arabia
Ali Alsuheel Asseri[SUP] 1 [/SUP], Mohammed Assiri[SUP] 2 [/SUP], Mohammed Abdullah Alshehri[SUP] 3 [/SUP], Malak Asseri[SUP] 4 [/SUP], Abdelwahid Saeed Ali[SUP] 5 [/SUP], Nabil J Awadalla[SUP] 6 [/SUP]
Affiliations
Abstract
Coronavirus disease-2019 (COVID-19) is a global health crisis that has impacted the world with heavy economic and social losses. In the early days of the pandemic, pediatric COVID-19 was well known for its low infectivity and mortality rates, as well as its benign clinical outcomes. Herein, we report the case of a 6-year-old girl with COVID-19-associated encephalopathy without respiratory symptoms. To our knowledge, this is the first child reported from Saudi Arabia with COVID-19 induced encephalopathy. Case: A 6-year-old patient with COVID-19 was presented to the Abha Maternity and Child Hospital (AMCH) in Southeastern Saudi Arabia. Routine clinical and laboratory examinations revealed normal findings. Despite the absence of COVID-19 respiratory manifestations, the patient manifested COVID-19-related encephalopathy. The patient responded well to pulse steroid, favipiravir, and symptomatic seizure therapies. The patient recovered completely, without any neurological morbidities. Conclusion: A COVID-19-related encephalopathy was observed for the first time in Saudi Arabia among pediatric patients. Clinicians should be alert to potential neurologic complications associated with COVID-19. It should be considered in the differential diagnosis of children presenting with acute encephalopathy, even in the absence of respiratory symptoms. To avoid long-term neurological sequelae, prompt seizure and immunosuppressive therapies are essential.
Keywords: COVID-19; children; encephalopathy; status epilepticus.
. 2022 Aug 20;S1201-9712(22)00483-0.
doi: 10.1016/j.ijid.2022.08.013. Online ahead of print.
Acute Encephalopathy in a 6-Year-Old Child with Concurrent Coronavirus Disease-2019 Infection: A Case Report from Saudi Arabia
Ali Alsuheel Asseri[SUP] 1 [/SUP], Mohammed Assiri[SUP] 2 [/SUP], Mohammed Abdullah Alshehri[SUP] 3 [/SUP], Malak Asseri[SUP] 4 [/SUP], Abdelwahid Saeed Ali[SUP] 5 [/SUP], Nabil J Awadalla[SUP] 6 [/SUP]
Affiliations
- PMID: 35998873
- DOI: 10.1016/j.ijid.2022.08.013
Abstract
Coronavirus disease-2019 (COVID-19) is a global health crisis that has impacted the world with heavy economic and social losses. In the early days of the pandemic, pediatric COVID-19 was well known for its low infectivity and mortality rates, as well as its benign clinical outcomes. Herein, we report the case of a 6-year-old girl with COVID-19-associated encephalopathy without respiratory symptoms. To our knowledge, this is the first child reported from Saudi Arabia with COVID-19 induced encephalopathy. Case: A 6-year-old patient with COVID-19 was presented to the Abha Maternity and Child Hospital (AMCH) in Southeastern Saudi Arabia. Routine clinical and laboratory examinations revealed normal findings. Despite the absence of COVID-19 respiratory manifestations, the patient manifested COVID-19-related encephalopathy. The patient responded well to pulse steroid, favipiravir, and symptomatic seizure therapies. The patient recovered completely, without any neurological morbidities. Conclusion: A COVID-19-related encephalopathy was observed for the first time in Saudi Arabia among pediatric patients. Clinicians should be alert to potential neurologic complications associated with COVID-19. It should be considered in the differential diagnosis of children presenting with acute encephalopathy, even in the absence of respiratory symptoms. To avoid long-term neurological sequelae, prompt seizure and immunosuppressive therapies are essential.
Keywords: COVID-19; children; encephalopathy; status epilepticus.