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Int J Hematol . Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan

tetano

Editor, Senior Moderator
Int J Hematol


. 2022 Sep 4.
doi: 10.1007/s12185-022-03445-2. Online ahead of print.
Case reports of management of aplastic anemia after COVID-19 vaccination: a single institute experience in Taiwan


Chia-Yu Chen[SUP] 1 [/SUP], Tzu-Ting Chen[SUP] 1 [/SUP], Ching-Yun Hsieh[SUP] 1 [/SUP], Ming-Yu Lien[SUP] 1 2 [/SUP], Su-Peng Yeh[SUP] 1 2 [/SUP], Chi-Ching Chen[SUP] 3 [/SUP]



Affiliations

Abstract

Global vaccination against the coronavirus disease 2019 (COVID-19) is thought to be the most effective way to end or at least contain the COVID-19 pandemic. However, despite the good safety profiles and effectiveness of the available COVID-19 vaccines, rare but serious hematological complications have emerged, including thromboembolic outcomes with thrombocytopenia following the ChAdOx1 nCoV-19 (Oxford-AstraZeneca) and Ad26.COV.2.S (Johnson & Johnson/Janssen) vaccines. Moreover, COVID-19 vaccination may be linked to the development of aplastic anemia (AA). We discuss four cases of AA that arose after COVID-19 vaccination in our hospital and two other such cases identified in our literature review.

Keywords: Aplastic anemia; COVID-19; Coronavirus disease 2019; SARS-CoV-2; Severe acute respiratory syndrome coronavirus-2 vaccine; Vaccination.
 
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