tetano
Editor, Senior Moderator
Int J Gynaecol Obstet
. 2020 Nov 1.
doi: 10.1002/ijgo.13460. Online ahead of print.
Updated experience of a tertiary pandemic center on 533 pregnant women with COVID-19 infection: A prospective cohort study from Turkey
Dilek Sahin[SUP] 1 [/SUP], Atakan Tanacan[SUP] 2 [/SUP], Seyit A Erol[SUP] 2 [/SUP], Ali T Anuk[SUP] 2 [/SUP], Fatma D Y Yetiskin[SUP] 2 [/SUP], Huseyin L Keskin[SUP] 1 [/SUP], Namik Ozcan[SUP] 3 [/SUP], A Seval Ozgu-Erdinc[SUP] 2 [/SUP], Elif G Y Eyi[SUP] 2 [/SUP], Aykan Yucel[SUP] 1 [/SUP], Cuneyt Tayman[SUP] 4 [/SUP], Serpil Unlu[SUP] 5 [/SUP], Bedia Dinc[SUP] 6 [/SUP], Eyup Sari[SUP] 7 [/SUP], Aziz A Surel[SUP] 8 [/SUP], Ozlem T Moraloglu[SUP] 1 9 [/SUP]
Affiliations
Abstract
Objective: To investigate the clinical course and impact of coronavirus disease 2019 (COVID-19) infection on pregnant women.
Methods: A prospective cohort study was conducted on pregnant women with confirmed COVID-19 infection. Demographic features, clinical characteristics, and perinatal outcomes were prospectively evaluated.
Results: Of the 533 cases, 161 (30.2%) had co-morbidities and 165 (30.9%) were asymptomatic. Cough (n=178, 33.4%) and myalgia (n=168, 31.5%) were the leading symptoms. In total, 261 patients (48.9%) received COVID-19 therapy, 509 (95.5%) had mild disease, 7 (1.3%) were admitted to the intensive care unit (ICU), and invasive mechanical ventilation was necessary in 2 (0.4%) patients. Maternal mortality was observed in 2 (0.4%) cases. Of the patients, 297 (55.7%) were hospitalized, 39 (7.3%) had suspicious radiologic imaging findings, 66 (12.4) had pregnancy complications (preterm delivery [n=22, 4.1%] and miscarriage [n=12, 2.2%] were the most common pregnancy complications), 131 births occurred, and the cesarean section rate was 66.4%. All neonates were negative for COVID-19. The rate of admission to the neonatal ICU was 9.9%. One specimen of breast milk was positive for the infection.
Conclusion: The course of COVID-19 was mild in the majority of cases. However, increased rates of pregnancy complications and cesarean delivery were observed.
Keywords: COVID-19; Pandemic; Perinatal outcomes; Pregnancy; SARS-CoV-2.
. 2020 Nov 1.
doi: 10.1002/ijgo.13460. Online ahead of print.
Updated experience of a tertiary pandemic center on 533 pregnant women with COVID-19 infection: A prospective cohort study from Turkey
Dilek Sahin[SUP] 1 [/SUP], Atakan Tanacan[SUP] 2 [/SUP], Seyit A Erol[SUP] 2 [/SUP], Ali T Anuk[SUP] 2 [/SUP], Fatma D Y Yetiskin[SUP] 2 [/SUP], Huseyin L Keskin[SUP] 1 [/SUP], Namik Ozcan[SUP] 3 [/SUP], A Seval Ozgu-Erdinc[SUP] 2 [/SUP], Elif G Y Eyi[SUP] 2 [/SUP], Aykan Yucel[SUP] 1 [/SUP], Cuneyt Tayman[SUP] 4 [/SUP], Serpil Unlu[SUP] 5 [/SUP], Bedia Dinc[SUP] 6 [/SUP], Eyup Sari[SUP] 7 [/SUP], Aziz A Surel[SUP] 8 [/SUP], Ozlem T Moraloglu[SUP] 1 9 [/SUP]
Affiliations
- PMID: 33131057
- DOI: 10.1002/ijgo.13460
Abstract
Objective: To investigate the clinical course and impact of coronavirus disease 2019 (COVID-19) infection on pregnant women.
Methods: A prospective cohort study was conducted on pregnant women with confirmed COVID-19 infection. Demographic features, clinical characteristics, and perinatal outcomes were prospectively evaluated.
Results: Of the 533 cases, 161 (30.2%) had co-morbidities and 165 (30.9%) were asymptomatic. Cough (n=178, 33.4%) and myalgia (n=168, 31.5%) were the leading symptoms. In total, 261 patients (48.9%) received COVID-19 therapy, 509 (95.5%) had mild disease, 7 (1.3%) were admitted to the intensive care unit (ICU), and invasive mechanical ventilation was necessary in 2 (0.4%) patients. Maternal mortality was observed in 2 (0.4%) cases. Of the patients, 297 (55.7%) were hospitalized, 39 (7.3%) had suspicious radiologic imaging findings, 66 (12.4) had pregnancy complications (preterm delivery [n=22, 4.1%] and miscarriage [n=12, 2.2%] were the most common pregnancy complications), 131 births occurred, and the cesarean section rate was 66.4%. All neonates were negative for COVID-19. The rate of admission to the neonatal ICU was 9.9%. One specimen of breast milk was positive for the infection.
Conclusion: The course of COVID-19 was mild in the majority of cases. However, increased rates of pregnancy complications and cesarean delivery were observed.
Keywords: COVID-19; Pandemic; Perinatal outcomes; Pregnancy; SARS-CoV-2.