tetano
Editor, Senior Moderator
Int J Gynaecol Obstet
. 2021 Nov 12.
doi: 10.1002/ijgo.14018. Online ahead of print.
Incidence of influenza and other respiratory viruses among pregnant women; a multi-country, multiyear cohort
Eduardo Azziz-Baumgartner[SUP] 1 [/SUP], Vic Veguilla[SUP] 1 [/SUP], Arlene Calvo[SUP] 2 [/SUP], Danilo Franco[SUP] 3 [/SUP], Rhina Dominguez[SUP] 4 [/SUP], Rafael Rauda[SUP] 4 [/SUP], Julio Armero[SUP] 4 [/SUP], Aron J Hall[SUP] 1 [/SUP], Juan Miguel Pascale[SUP] 3 [/SUP], Rosalba Gonzalez[SUP] 3 [/SUP]
Affiliations
Abstract
Objective: To quantify rates of influenza illness and assess value of influenza vaccination among pregnant women in Panama and El Salvador.
Methods: Pregnant women were enrolled and followed each week in a prospective cohort study to identify acute respiratory infections (ARI). Nasopharyngeal swabs obtained from women with febrile ARI were tested by reverse-transcription polymerase chain reaction for influenza and other respiratory viruses.
Results: We enrolled 2,556 women between October 2014-April 2017. Sixteen percent developed at least one ARI; 59 had two ARI, and five had three ARI for a total of 463 ARI. Women in El Salvador and Panama contributed 297 person-years (py) and 293py, respectively, during influenza circulation. Twenty-one (11%) of 196 sampled women tested positive for influenza. Influenza incidence was 5.0/100py (4.3/100py in Panama and 5.7/100py in El Salvador). Only 13% of women in El Salvador and 43% in Panama had been vaccinated against influenza before influenza epidemics (p<0.0001).
Conclusions: One in six pregnant women developed ARI and more than one in ten ARI were attributable to vaccine-preventable influenza. While women were at risk of influenza, few had vaccinated before each epidemic. Such findings suggest the utility of evaluations to optimize vaccine timing and coverage.
Keywords: infection; influenza; pregnant; respiratory; syncytial; vaccine; virus; women.
. 2021 Nov 12.
doi: 10.1002/ijgo.14018. Online ahead of print.
Incidence of influenza and other respiratory viruses among pregnant women; a multi-country, multiyear cohort
Eduardo Azziz-Baumgartner[SUP] 1 [/SUP], Vic Veguilla[SUP] 1 [/SUP], Arlene Calvo[SUP] 2 [/SUP], Danilo Franco[SUP] 3 [/SUP], Rhina Dominguez[SUP] 4 [/SUP], Rafael Rauda[SUP] 4 [/SUP], Julio Armero[SUP] 4 [/SUP], Aron J Hall[SUP] 1 [/SUP], Juan Miguel Pascale[SUP] 3 [/SUP], Rosalba Gonzalez[SUP] 3 [/SUP]
Affiliations
- PMID: 34767628
- DOI: 10.1002/ijgo.14018
Abstract
Objective: To quantify rates of influenza illness and assess value of influenza vaccination among pregnant women in Panama and El Salvador.
Methods: Pregnant women were enrolled and followed each week in a prospective cohort study to identify acute respiratory infections (ARI). Nasopharyngeal swabs obtained from women with febrile ARI were tested by reverse-transcription polymerase chain reaction for influenza and other respiratory viruses.
Results: We enrolled 2,556 women between October 2014-April 2017. Sixteen percent developed at least one ARI; 59 had two ARI, and five had three ARI for a total of 463 ARI. Women in El Salvador and Panama contributed 297 person-years (py) and 293py, respectively, during influenza circulation. Twenty-one (11%) of 196 sampled women tested positive for influenza. Influenza incidence was 5.0/100py (4.3/100py in Panama and 5.7/100py in El Salvador). Only 13% of women in El Salvador and 43% in Panama had been vaccinated against influenza before influenza epidemics (p<0.0001).
Conclusions: One in six pregnant women developed ARI and more than one in ten ARI were attributable to vaccine-preventable influenza. While women were at risk of influenza, few had vaccinated before each epidemic. Such findings suggest the utility of evaluations to optimize vaccine timing and coverage.
Keywords: infection; influenza; pregnant; respiratory; syncytial; vaccine; virus; women.