tetano
Editor, Senior Moderator
Int J Equity Health
. 2020 Jul 6;19(1):114.
doi: 10.1186/s12939-020-01227-y.
Race, Socioeconomic Deprivation, and Hospitalization for COVID-19 in English Participants of a National Biobank
Aniruddh P Patel[SUP] 1 2 3 [/SUP], Manish D Paranjpe[SUP] 2 3 [/SUP], Nina P Kathiresan[SUP] 3 4 [/SUP], Manuel A Rivas[SUP] 5 [/SUP], Amit V Khera[SUP] 6 7 8 [/SUP]
Affiliations
Abstract
Preliminary reports suggest that the Coronavirus Disease 2019 (COVID- 19) pandemic has led to disproportionate morbidity and mortality among historically disadvantaged populations. We investigate the racial and socioeconomic associations of COVID- 19 hospitalization among 418,794 participants of the UK Biobank, of whom 549 (0.13%) had been hospitalized. Both Black participants (odds ratio 3.7; 95%CI 2.5-5.3) and Asian participants (odds ratio 2.2; 95%CI 1.5-3.2) were at substantially increased risk as compared to White participants. We further observed a striking gradient in COVID- 19 hospitalization rates according to the Townsend Deprivation Index - a composite measure of socioeconomic deprivation - and household income. Adjusting for socioeconomic factors and cardiorespiratory comorbidities led to only modest attenuation of the increased risk in Black participants, adjusted odds ratio 2.4 (95%CI 1.5-3.7). These observations confirm and extend earlier preliminary and lay press reports of higher morbidity in non-White individuals in the context of a large population of participants in a national biobank. The extent to which this increased risk relates to variation in pre-existing comorbidities, differences in testing or hospitalization patterns, or additional disparities in social determinants of health warrants further study.
Keywords: COVID-19; Health disparity; Race; Socioeconomic deprivation.
. 2020 Jul 6;19(1):114.
doi: 10.1186/s12939-020-01227-y.
Race, Socioeconomic Deprivation, and Hospitalization for COVID-19 in English Participants of a National Biobank
Aniruddh P Patel[SUP] 1 2 3 [/SUP], Manish D Paranjpe[SUP] 2 3 [/SUP], Nina P Kathiresan[SUP] 3 4 [/SUP], Manuel A Rivas[SUP] 5 [/SUP], Amit V Khera[SUP] 6 7 8 [/SUP]
Affiliations
- PMID: 32631328
- DOI: 10.1186/s12939-020-01227-y
Abstract
Preliminary reports suggest that the Coronavirus Disease 2019 (COVID- 19) pandemic has led to disproportionate morbidity and mortality among historically disadvantaged populations. We investigate the racial and socioeconomic associations of COVID- 19 hospitalization among 418,794 participants of the UK Biobank, of whom 549 (0.13%) had been hospitalized. Both Black participants (odds ratio 3.7; 95%CI 2.5-5.3) and Asian participants (odds ratio 2.2; 95%CI 1.5-3.2) were at substantially increased risk as compared to White participants. We further observed a striking gradient in COVID- 19 hospitalization rates according to the Townsend Deprivation Index - a composite measure of socioeconomic deprivation - and household income. Adjusting for socioeconomic factors and cardiorespiratory comorbidities led to only modest attenuation of the increased risk in Black participants, adjusted odds ratio 2.4 (95%CI 1.5-3.7). These observations confirm and extend earlier preliminary and lay press reports of higher morbidity in non-White individuals in the context of a large population of participants in a national biobank. The extent to which this increased risk relates to variation in pre-existing comorbidities, differences in testing or hospitalization patterns, or additional disparities in social determinants of health warrants further study.
Keywords: COVID-19; Health disparity; Race; Socioeconomic deprivation.