tetano
Editor, Senior Moderator
Int J Epidemiol
. 2020 Jun 30;dyaa106.
doi: 10.1093/ije/dyaa106. Online ahead of print.
Epidemiological Characteristics of the First 100 Cases of Coronavirus Disease 2019 (COVID-19) in Hong Kong Special Administrative Region, China, a City With a Stringent Containment Policy
Christopher K C Lai[SUP] 1 [/SUP], Rita W Y Ng[SUP] 1 [/SUP], Martin C S Wong[SUP] 2 [/SUP], Ka Chun Chong[SUP] 2 3 [/SUP], Yun Kit Yeoh[SUP] 1 [/SUP], Zigui Chen[SUP] 1 [/SUP], Paul K S Chan[SUP] 1 [/SUP]
AffiliationsExpand
Abstract
Background: Hong Kong (HK) is a densely populated city near the epicentre of the coronavirus disease 2019 (COVID-19) outbreak. Stringent border control together with aggressive case finding, contact tracing, social distancing and quarantine measures were implemented to halt the importation and spread of the virus.
Methods: We performed an epidemiological study using government information covering the first 100 confirmed cases to examine the epidemic curve, incidence, clusters, reproduction number (Rt), incubation period and time to containment.
Results: A total of 93 of the 100 cases were HK residents (6 infected in Mainland China, 10 on the Diamond Princess Cruise). Seven were visitors infected in Mainland China before entering HK. The majority (76%) were aged ≥45 years, and the incidence increased with age (P < 0.001). Escalation of border control measures correlated with a decrease in the proportion (62.5% to 0%) of cases imported from Mainland China, and a reduction in Rt (1.07 to 0.75). The median incubation period was 4.2 days [95% confidence interval (CI), 4.0-4.5; 5th and 95th percentiles: 1.3 and 14.0). Most clusters with identifiable epidemiological links were households involving 2-4 people. Three medium-spreading events were identified: two from New Year gatherings (6-11 people), and another from environmental contamination of a worship hall (12 people). Despite intensified contact tracing, containment was delayed in 78.9% of cases (mean = 5.96 days, range = 0-24 days). An unusual transmission in a multi-storey building via faulty toilet plumbing was suspected with >100 residents evacuated overnight. Our analysis indicated that faulty plumbing was unlikely to be the source of this transmission.
Conclusions: Timely stringent containment policies minimized the importation and transmission of COVID-19 in HK.
Keywords: COVID-19; containment policy; epidemic curve; novel coronavirus; social distancing measures.
. 2020 Jun 30;dyaa106.
doi: 10.1093/ije/dyaa106. Online ahead of print.
Epidemiological Characteristics of the First 100 Cases of Coronavirus Disease 2019 (COVID-19) in Hong Kong Special Administrative Region, China, a City With a Stringent Containment Policy
Christopher K C Lai[SUP] 1 [/SUP], Rita W Y Ng[SUP] 1 [/SUP], Martin C S Wong[SUP] 2 [/SUP], Ka Chun Chong[SUP] 2 3 [/SUP], Yun Kit Yeoh[SUP] 1 [/SUP], Zigui Chen[SUP] 1 [/SUP], Paul K S Chan[SUP] 1 [/SUP]
AffiliationsExpand
- PMID: 32601677
- DOI: 10.1093/ije/dyaa106
Abstract
Background: Hong Kong (HK) is a densely populated city near the epicentre of the coronavirus disease 2019 (COVID-19) outbreak. Stringent border control together with aggressive case finding, contact tracing, social distancing and quarantine measures were implemented to halt the importation and spread of the virus.
Methods: We performed an epidemiological study using government information covering the first 100 confirmed cases to examine the epidemic curve, incidence, clusters, reproduction number (Rt), incubation period and time to containment.
Results: A total of 93 of the 100 cases were HK residents (6 infected in Mainland China, 10 on the Diamond Princess Cruise). Seven were visitors infected in Mainland China before entering HK. The majority (76%) were aged ≥45 years, and the incidence increased with age (P < 0.001). Escalation of border control measures correlated with a decrease in the proportion (62.5% to 0%) of cases imported from Mainland China, and a reduction in Rt (1.07 to 0.75). The median incubation period was 4.2 days [95% confidence interval (CI), 4.0-4.5; 5th and 95th percentiles: 1.3 and 14.0). Most clusters with identifiable epidemiological links were households involving 2-4 people. Three medium-spreading events were identified: two from New Year gatherings (6-11 people), and another from environmental contamination of a worship hall (12 people). Despite intensified contact tracing, containment was delayed in 78.9% of cases (mean = 5.96 days, range = 0-24 days). An unusual transmission in a multi-storey building via faulty toilet plumbing was suspected with >100 residents evacuated overnight. Our analysis indicated that faulty plumbing was unlikely to be the source of this transmission.
Conclusions: Timely stringent containment policies minimized the importation and transmission of COVID-19 in HK.
Keywords: COVID-19; containment policy; epidemic curve; novel coronavirus; social distancing measures.