tetano
Editor, Senior Moderator
Int J Environ Res Public Health
. 2022 Mar 1;19(5):2877.
doi: 10.3390/ijerph19052877.
Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials
Alvaro Garcia-Sanchez[SUP] 1 [/SUP], Juan-Francisco Peña-Cardelles[SUP] 2 3 4 [/SUP], Esther Ordonez-Fernandez[SUP] 5 [/SUP], María Montero-Alonso[SUP] 6 [/SUP], Naresh Kewalramani[SUP] 7 [/SUP], Angel-Orión Salgado-Peralvo[SUP] 8 [/SUP], Dániel Végh[SUP] 9 10 [/SUP], Angélica Gargano[SUP] 5 [/SUP], Gabriela Parra[SUP] 5 [/SUP], Lourdes-Isabela Guerra-Guajardo[SUP] 5 [/SUP], Wataru Kozuma[SUP] 4 11 [/SUP]
Affiliations
Abstract
The use of pre-procedural rinses has been investigated to reduce the number of viral particles and bacteria in aerosols, potentially decreasing the risk of cross-infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during medical and dental procedures. This review aims to confirm whether there is evidence in the literature describing a reduction in salivary load of SARS-CoV-2 when povidone-iodine (PVP-I) is used as a pre-intervention mouthwash. An search of the MEDLINE, Embase, SCOPUS, and the Cochrane library databases was conducted. The criteria used followed the PRISMA[SUP]®[/SUP] Statement guidelines. Randomized controlled trials investigating the reduction of salivary load of SARS-CoV-2 using PVP-I were included. Ultimately, four articles were included that met the established criteria. According to the current evidence, PVP-I is effective against SARS-CoV-2 in saliva and could be implemented as a rinse before interventions to decrease the risk of cross-infection in healthcare settings.
Keywords: COVID-19; SARS-CoV-2; aerosols; cetylpiridinium chloride; chlorhexidine; colony-forming units; hydrogen peroxide; mouthrinse; mouthwashes; povidone-iodine.
. 2022 Mar 1;19(5):2877.
doi: 10.3390/ijerph19052877.
Povidone-Iodine as a Pre-Procedural Mouthwash to Reduce the Salivary Viral Load of SARS-CoV-2: A Systematic Review of Randomized Controlled Trials
Alvaro Garcia-Sanchez[SUP] 1 [/SUP], Juan-Francisco Peña-Cardelles[SUP] 2 3 4 [/SUP], Esther Ordonez-Fernandez[SUP] 5 [/SUP], María Montero-Alonso[SUP] 6 [/SUP], Naresh Kewalramani[SUP] 7 [/SUP], Angel-Orión Salgado-Peralvo[SUP] 8 [/SUP], Dániel Végh[SUP] 9 10 [/SUP], Angélica Gargano[SUP] 5 [/SUP], Gabriela Parra[SUP] 5 [/SUP], Lourdes-Isabela Guerra-Guajardo[SUP] 5 [/SUP], Wataru Kozuma[SUP] 4 11 [/SUP]
Affiliations
- PMID: 35270569
- DOI: 10.3390/ijerph19052877
Abstract
The use of pre-procedural rinses has been investigated to reduce the number of viral particles and bacteria in aerosols, potentially decreasing the risk of cross-infection from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during medical and dental procedures. This review aims to confirm whether there is evidence in the literature describing a reduction in salivary load of SARS-CoV-2 when povidone-iodine (PVP-I) is used as a pre-intervention mouthwash. An search of the MEDLINE, Embase, SCOPUS, and the Cochrane library databases was conducted. The criteria used followed the PRISMA[SUP]®[/SUP] Statement guidelines. Randomized controlled trials investigating the reduction of salivary load of SARS-CoV-2 using PVP-I were included. Ultimately, four articles were included that met the established criteria. According to the current evidence, PVP-I is effective against SARS-CoV-2 in saliva and could be implemented as a rinse before interventions to decrease the risk of cross-infection in healthcare settings.
Keywords: COVID-19; SARS-CoV-2; aerosols; cetylpiridinium chloride; chlorhexidine; colony-forming units; hydrogen peroxide; mouthrinse; mouthwashes; povidone-iodine.