tetano
Editor, Senior Moderator
Int J Clin Pract
. 2021 Sep 4;e14786.
doi: 10.1111/ijcp.14786. Online ahead of print.
Characteristics of Hospitalized COVID-19 Patients and Parameters Associated with Severe Pneumonia
Onur Turan[SUP] 1 [/SUP], Arzu Mirici[SUP] 2 [/SUP], Serap Duru Akçalı[SUP] 3 [/SUP], Pakize Ayşe Turan[SUP] 4 [/SUP], Özgür Batum[SUP] 5 [/SUP], Aysun Şengül[SUP] 6 [/SUP], Zühal Ekici Ünsal[SUP] 7 [/SUP], Nalan Işık Kabakoğlu[SUP] 8 [/SUP], Nalan Ogan[SUP] 9 [/SUP], Şerife Torun[SUP] 10 [/SUP], A K Güntülü[SUP] 11 [/SUP], Şule Akçay[SUP] 12 [/SUP], Berna Kömürcüoğlu[SUP] 5 [/SUP], Nazan Şen[SUP] 13 [/SUP], Pınar Mutlu[SUP] 2 [/SUP], Ülkü Yılmaz[SUP] 14 [/SUP]
Affiliations
Abstract
Background: After the first case of coronavirus disease-2019 (COVID-19) was reported in China in December 2019, it caused a global pandemic, including Turkey.
Objectives: The aim of this study is to analyze the characteristics of hospitalized COVID-19 patients and assess the parameters related with severe pneumonia.
Methods: Included in the study were hospitalized COVID-19 patients with positive naso-oropharyngeal swabs. Patients' demographics, admission symptoms, laboratory and radiological findings were recorded retrospectively.
Results: Of 1013 patients, 583 were male (57.6%) and 430 were female (42.4%), with a mean age of 53.7±17.9. More than half of the patients had at least one comorbidities, the most common of which were hypertension and diabetes mellitus. Cough (59.8%), fatigue (49.5%) and fever (41.2%) were the most common presenting symptoms. Of the hospitalized COVID-19 patients, 84.9% had pneumonia, and 83.5% had typical radiological COVID-19 appearances (94.5%: ground glass areas). The most common laboratory findings were high C-reactive protein (CRP) (73.6%) and lactate dehydrogenase (LDH) (46.2%) levels, as well as lymphopenia (30.1%). Severe pneumonia was present in 28.1% of COVID-19 patients. Multivariate logistic regression analysis indicated that advanced age, hypotension, anemia, and elevated CRP and LDH serum levels were independent risk factors for the severity of COVID-19 pneumonia (p=0.011, 0.006, 0.017, 0.003 and 0.001, respectively).
Conclusion: The present study,as one of the first multicenter studies about characteristics of COVID-19 in Turkey, may guide about disease-related parameters and severity of pneumonia. Age, blood pressure, complete blood count and routine biochemical tests (including CRP and LDH) would appear to be important parameters for the evaluation of the severity of COVID-19 pneumonia.
Keywords: COVID-19; laboratory features; pneumonia; radiological findings; symptoms.
. 2021 Sep 4;e14786.
doi: 10.1111/ijcp.14786. Online ahead of print.
Characteristics of Hospitalized COVID-19 Patients and Parameters Associated with Severe Pneumonia
Onur Turan[SUP] 1 [/SUP], Arzu Mirici[SUP] 2 [/SUP], Serap Duru Akçalı[SUP] 3 [/SUP], Pakize Ayşe Turan[SUP] 4 [/SUP], Özgür Batum[SUP] 5 [/SUP], Aysun Şengül[SUP] 6 [/SUP], Zühal Ekici Ünsal[SUP] 7 [/SUP], Nalan Işık Kabakoğlu[SUP] 8 [/SUP], Nalan Ogan[SUP] 9 [/SUP], Şerife Torun[SUP] 10 [/SUP], A K Güntülü[SUP] 11 [/SUP], Şule Akçay[SUP] 12 [/SUP], Berna Kömürcüoğlu[SUP] 5 [/SUP], Nazan Şen[SUP] 13 [/SUP], Pınar Mutlu[SUP] 2 [/SUP], Ülkü Yılmaz[SUP] 14 [/SUP]
Affiliations
- PMID: 34480831
- DOI: 10.1111/ijcp.14786
Abstract
Background: After the first case of coronavirus disease-2019 (COVID-19) was reported in China in December 2019, it caused a global pandemic, including Turkey.
Objectives: The aim of this study is to analyze the characteristics of hospitalized COVID-19 patients and assess the parameters related with severe pneumonia.
Methods: Included in the study were hospitalized COVID-19 patients with positive naso-oropharyngeal swabs. Patients' demographics, admission symptoms, laboratory and radiological findings were recorded retrospectively.
Results: Of 1013 patients, 583 were male (57.6%) and 430 were female (42.4%), with a mean age of 53.7±17.9. More than half of the patients had at least one comorbidities, the most common of which were hypertension and diabetes mellitus. Cough (59.8%), fatigue (49.5%) and fever (41.2%) were the most common presenting symptoms. Of the hospitalized COVID-19 patients, 84.9% had pneumonia, and 83.5% had typical radiological COVID-19 appearances (94.5%: ground glass areas). The most common laboratory findings were high C-reactive protein (CRP) (73.6%) and lactate dehydrogenase (LDH) (46.2%) levels, as well as lymphopenia (30.1%). Severe pneumonia was present in 28.1% of COVID-19 patients. Multivariate logistic regression analysis indicated that advanced age, hypotension, anemia, and elevated CRP and LDH serum levels were independent risk factors for the severity of COVID-19 pneumonia (p=0.011, 0.006, 0.017, 0.003 and 0.001, respectively).
Conclusion: The present study,as one of the first multicenter studies about characteristics of COVID-19 in Turkey, may guide about disease-related parameters and severity of pneumonia. Age, blood pressure, complete blood count and routine biochemical tests (including CRP and LDH) would appear to be important parameters for the evaluation of the severity of COVID-19 pneumonia.
Keywords: COVID-19; laboratory features; pneumonia; radiological findings; symptoms.