tetano
Editor, Senior Moderator
Int J Cardiovasc Imaging
. 2021 Aug 13.
doi: 10.1007/s10554-021-02376-z. Online ahead of print.
Left ventricular global longitudinal strain in low cardiac risk outpatients who recently recovered from coronavirus disease 2019
Turhan Turan[SUP] 1 [/SUP], Ahmet Özderya[SUP] 2 [/SUP], Sinan Şahin[SUP] 2 [/SUP], Ali Hakan Konuş[SUP] 2 [/SUP], Selim Kul[SUP] 2 [/SUP], Ali Rıza Akyüz[SUP] 2 [/SUP], Ezgi Kalaycıoğlu[SUP] 2 [/SUP], Muhammet Raşit Sayın[SUP] 2 [/SUP]
Affiliations
Abstract
The cardiac sequelae of coronavirus disease 2019 (COVID-19), a worldwide global pandemic, are still uncertain, particularly in the asymptomatic, low cardiac risk outpatient population. This study aims to evaluate the asymptomatic, low cardiac risk out-patient population who recently recovered from COVID-19, using 2-D left ventricular-global longitudinal strain (LV-GLS) proven to be capable of detecting subclinical myocardial injury. Out of 305 COVID-19 positive patients, 70 asymptomatic out-patients were determined as the study group and 70 age and sex-matched healthy adults as the control group. The echocardiographic examination was performed with the Philips IE33 system, and LV-GLS was measured using commercially available software QLAB 9 (cardiac motion quantification; Philips Medical Systems). The absolute value of LV-GLS ≤ 18 did deem to be impaired LV-GLS. The absolute value of LV-GLS was statistically significantly lower in the COVID-19 group than in healthy controls (19.17 ± 2.65 vs. 20.07 ± 2.19, p = 0.03). The correlation between having recovered from COVID-19 and impaired LV-GLS (≤18) did detect with the Pearson correlation test (p = 0.02). Having recovered from COVID-19 was found as a predictor for detecting impaired LV-GLS (≤18) in the multivariable logistic regression analysis (odds ratio, 0.133 (0.038-0.461); 95% CI, p = 0.001). This study suggests that COVID-19 may cause subclinical LV dysfunction detected by LV-GLS during early recovery even in a population of patients at low cardiac risk, asymptomatic, and recovered with home quarantine. The study findings indicate that the long-term cardiovascular follow-up of these patients may be more important than thought.
Keywords: Home quarantine; Low cardiac risk; SARS coronavirus; Ventricular global longitudinal strain.
. 2021 Aug 13.
doi: 10.1007/s10554-021-02376-z. Online ahead of print.
Left ventricular global longitudinal strain in low cardiac risk outpatients who recently recovered from coronavirus disease 2019
Turhan Turan[SUP] 1 [/SUP], Ahmet Özderya[SUP] 2 [/SUP], Sinan Şahin[SUP] 2 [/SUP], Ali Hakan Konuş[SUP] 2 [/SUP], Selim Kul[SUP] 2 [/SUP], Ali Rıza Akyüz[SUP] 2 [/SUP], Ezgi Kalaycıoğlu[SUP] 2 [/SUP], Muhammet Raşit Sayın[SUP] 2 [/SUP]
Affiliations
- PMID: 34387799
- DOI: 10.1007/s10554-021-02376-z
Abstract
The cardiac sequelae of coronavirus disease 2019 (COVID-19), a worldwide global pandemic, are still uncertain, particularly in the asymptomatic, low cardiac risk outpatient population. This study aims to evaluate the asymptomatic, low cardiac risk out-patient population who recently recovered from COVID-19, using 2-D left ventricular-global longitudinal strain (LV-GLS) proven to be capable of detecting subclinical myocardial injury. Out of 305 COVID-19 positive patients, 70 asymptomatic out-patients were determined as the study group and 70 age and sex-matched healthy adults as the control group. The echocardiographic examination was performed with the Philips IE33 system, and LV-GLS was measured using commercially available software QLAB 9 (cardiac motion quantification; Philips Medical Systems). The absolute value of LV-GLS ≤ 18 did deem to be impaired LV-GLS. The absolute value of LV-GLS was statistically significantly lower in the COVID-19 group than in healthy controls (19.17 ± 2.65 vs. 20.07 ± 2.19, p = 0.03). The correlation between having recovered from COVID-19 and impaired LV-GLS (≤18) did detect with the Pearson correlation test (p = 0.02). Having recovered from COVID-19 was found as a predictor for detecting impaired LV-GLS (≤18) in the multivariable logistic regression analysis (odds ratio, 0.133 (0.038-0.461); 95% CI, p = 0.001). This study suggests that COVID-19 may cause subclinical LV dysfunction detected by LV-GLS during early recovery even in a population of patients at low cardiac risk, asymptomatic, and recovered with home quarantine. The study findings indicate that the long-term cardiovascular follow-up of these patients may be more important than thought.
Keywords: Home quarantine; Low cardiac risk; SARS coronavirus; Ventricular global longitudinal strain.