tetano
Editor, Senior Moderator
Int J Cardiol
. 2021 Aug 17;S0167-5273(21)01228-6.
doi: 10.1016/j.ijcard.2021.08.018. Online ahead of print.
Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients
Antonio Abbate[SUP] 1 [/SUP], Josh Gavin[SUP] 2 [/SUP], Nima Madanchi[SUP] 2 [/SUP], Christin Kim[SUP] 3 [/SUP], Pranav R Shah[SUP] 3 [/SUP], Katherine Klein[SUP] 4 [/SUP], Julie Boatman[SUP] 5 [/SUP], Charlotte Roberts[SUP] 6 [/SUP], Seema Patel[SUP] 2 [/SUP], Stamatina Danielides[SUP] 7 [/SUP]
Affiliations
Abstract
Immune-mediated myocardial injury following Severe Acute Respiratory Syndrome Coronavirys-2 (SARS-CoV2) infection has been described in adults and children. Cases of myocarditis following immunization for SARS-CoV2 have recently been documented, mostly associated with mild severity and spontaneous recovery. We herein report two cases of fulminant myocarditis following BNT162b2 mRNA Covid-19 vaccination associated with systemic hyperinflammatory syndrome and refractory shock requiring support with veno-arterial extracorporeal membrane oxygenation.
Keywords: Coronavirus; Covid-19; Myocarditis; Vaccine.
. 2021 Aug 17;S0167-5273(21)01228-6.
doi: 10.1016/j.ijcard.2021.08.018. Online ahead of print.
Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients
Antonio Abbate[SUP] 1 [/SUP], Josh Gavin[SUP] 2 [/SUP], Nima Madanchi[SUP] 2 [/SUP], Christin Kim[SUP] 3 [/SUP], Pranav R Shah[SUP] 3 [/SUP], Katherine Klein[SUP] 4 [/SUP], Julie Boatman[SUP] 5 [/SUP], Charlotte Roberts[SUP] 6 [/SUP], Seema Patel[SUP] 2 [/SUP], Stamatina Danielides[SUP] 7 [/SUP]
Affiliations
- PMID: 34416319
- DOI: 10.1016/j.ijcard.2021.08.018
Abstract
Immune-mediated myocardial injury following Severe Acute Respiratory Syndrome Coronavirys-2 (SARS-CoV2) infection has been described in adults and children. Cases of myocarditis following immunization for SARS-CoV2 have recently been documented, mostly associated with mild severity and spontaneous recovery. We herein report two cases of fulminant myocarditis following BNT162b2 mRNA Covid-19 vaccination associated with systemic hyperinflammatory syndrome and refractory shock requiring support with veno-arterial extracorporeal membrane oxygenation.
Keywords: Coronavirus; Covid-19; Myocarditis; Vaccine.