tetano
Editor, Senior Moderator
Radiol Bras. 2019 Mar-Apr;52(2):78-84. doi: 10.1590/0100-3984.2018.0030.
[h=1]Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection.[/h] Ad?rno IF[SUP]1[/SUP], Tibana TK[SUP]1[/SUP], Santos RFT[SUP]1[/SUP], Le?o VMM[SUP]1[/SUP], Brustoloni YM[SUP]1[/SUP], Silva PAI[SUP]1[/SUP], Ferreira MA[SUP]1[/SUP], Nunes TF[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] in English, Portuguese
[h=4]Objective:[/h] To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection.
[h=4]Materials and Methods:[/h] We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 2016. The mean age of the patients was 14 months (range, 2-89 months). The diagnosis was established on the basis of clinical and radiographic criteria, and the virus was detected by polymerase chain reaction. The radiographic findings were categorized by type/pattern of opacity and by lung zone. The patients were divided into two groups: those not requiring ventilatory support; and those requiring ventilatory support or evolving to death.
[h=4]Results:[/h] The abnormality most often seen on chest X-rays was that of peribronchovascular opacities, the majority of which affected less than 25% of the lung, the involvement being bilateral and asymmetric. The lung zone most frequently involved was the middle third, with central and peripheral distribution, without pleural effusion. There was a statistically significant difference between the groups in terms of the symmetry of pulmonary involvement, asymmetric findings predominating in the group that required ventilatory support (p = 0.029).
[h=4]Conclusion:[/h] In pediatric patients with H1N1 virus infection, the main alterations on the initial chest X-rays are peribronchovascular opacities, nonspecific alveolar opacities, and consolidations. Although the definitive diagnosis of H1N1 virus infection cannot be made on the basis of imaging characteristics alone, using a combination of clinical and radiographic findings can substantially improve the diagnostic accuracy.
[h=4]KEYWORDS:[/h] Influenza A virus, H1N1 subtype; Influenza, human; Radiography, thoracic
PMID: 31019335 PMCID: PMC6472857 DOI: 10.1590/0100-3984.2018.0030
[h=1]Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection.[/h] Ad?rno IF[SUP]1[/SUP], Tibana TK[SUP]1[/SUP], Santos RFT[SUP]1[/SUP], Le?o VMM[SUP]1[/SUP], Brustoloni YM[SUP]1[/SUP], Silva PAI[SUP]1[/SUP], Ferreira MA[SUP]1[/SUP], Nunes TF[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] in English, Portuguese
[h=4]Objective:[/h] To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection.
[h=4]Materials and Methods:[/h] We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 2016. The mean age of the patients was 14 months (range, 2-89 months). The diagnosis was established on the basis of clinical and radiographic criteria, and the virus was detected by polymerase chain reaction. The radiographic findings were categorized by type/pattern of opacity and by lung zone. The patients were divided into two groups: those not requiring ventilatory support; and those requiring ventilatory support or evolving to death.
[h=4]Results:[/h] The abnormality most often seen on chest X-rays was that of peribronchovascular opacities, the majority of which affected less than 25% of the lung, the involvement being bilateral and asymmetric. The lung zone most frequently involved was the middle third, with central and peripheral distribution, without pleural effusion. There was a statistically significant difference between the groups in terms of the symmetry of pulmonary involvement, asymmetric findings predominating in the group that required ventilatory support (p = 0.029).
[h=4]Conclusion:[/h] In pediatric patients with H1N1 virus infection, the main alterations on the initial chest X-rays are peribronchovascular opacities, nonspecific alveolar opacities, and consolidations. Although the definitive diagnosis of H1N1 virus infection cannot be made on the basis of imaging characteristics alone, using a combination of clinical and radiographic findings can substantially improve the diagnostic accuracy.
[h=4]KEYWORDS:[/h] Influenza A virus, H1N1 subtype; Influenza, human; Radiography, thoracic
PMID: 31019335 PMCID: PMC6472857 DOI: 10.1590/0100-3984.2018.0030