tetano
Editor, Senior Moderator
J Sci Food Agric. 2017 Sep 13. doi: 10.1002/jsfa.8671. [Epub ahead of print]
[h=1]Inhibition of influenza virus replication by adlay tea.[/h] Nagai E[SUP]1,[/SUP][SUP]2[/SUP], Iwai M[SUP]1[/SUP], Koketsu R[SUP]3[/SUP], Sogabe R[SUP]1[/SUP], Morimoto R[SUP]1[/SUP], Suzuki Y[SUP]1[/SUP], Ohta Y[SUP]4[/SUP], Okuno Y[SUP]3[/SUP], Ohshima A[SUP]5[/SUP], Enomoto T[SUP]2[/SUP], Isegawa Y[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] This study was conducted to examine the antiviral activity of adlay tea and its components against influenza viruses. We further sought to clarify the mechanism by which these components regulate virus replication.
[h=4]RESULTS:[/h] Adlay tea at a concentration suitable for drinking inhibited the multiplication of influenza viruses. Moreover, our results suggested that individual components of the tea had antiviral activities against the influenza A/PR/8/34 virus. Adlay tea inhibited multiplication of the H1N1, H3N2, and B types of influenza virus, including oseltamivir-resistant viruses. In addition, adlay tea inhibited influenza infection during the periods of virus adsorption to the cell and virus replication. Adlay tea did not suppress hemoagglutination inhibition (HI) or cell fusion, although it slightly inhibited virus binding to MDCK cells. Furthermore, our findings suggested that the antiviral compounds included in adlay tea were other ingredients rather than polyphenols, and there were several kinds of effective compounds in adlay tea that inhibit several steps of viral replication.
[h=4]CONCLUSION:[/h] This study demonstrated that adlay tea had antiviral effects against influenza viruses. Our findings in adlay tea suggested that the polyphenols might have a small influence on its antiviral activity, and other ingredients might have more influence.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] adlay; antiviral effect; cassia seeds; influenza virus; naked barley; soybean
PMID: 28902408 DOI: 10.1002/jsfa.8671
[h=1]Inhibition of influenza virus replication by adlay tea.[/h] Nagai E[SUP]1,[/SUP][SUP]2[/SUP], Iwai M[SUP]1[/SUP], Koketsu R[SUP]3[/SUP], Sogabe R[SUP]1[/SUP], Morimoto R[SUP]1[/SUP], Suzuki Y[SUP]1[/SUP], Ohta Y[SUP]4[/SUP], Okuno Y[SUP]3[/SUP], Ohshima A[SUP]5[/SUP], Enomoto T[SUP]2[/SUP], Isegawa Y[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] This study was conducted to examine the antiviral activity of adlay tea and its components against influenza viruses. We further sought to clarify the mechanism by which these components regulate virus replication.
[h=4]RESULTS:[/h] Adlay tea at a concentration suitable for drinking inhibited the multiplication of influenza viruses. Moreover, our results suggested that individual components of the tea had antiviral activities against the influenza A/PR/8/34 virus. Adlay tea inhibited multiplication of the H1N1, H3N2, and B types of influenza virus, including oseltamivir-resistant viruses. In addition, adlay tea inhibited influenza infection during the periods of virus adsorption to the cell and virus replication. Adlay tea did not suppress hemoagglutination inhibition (HI) or cell fusion, although it slightly inhibited virus binding to MDCK cells. Furthermore, our findings suggested that the antiviral compounds included in adlay tea were other ingredients rather than polyphenols, and there were several kinds of effective compounds in adlay tea that inhibit several steps of viral replication.
[h=4]CONCLUSION:[/h] This study demonstrated that adlay tea had antiviral effects against influenza viruses. Our findings in adlay tea suggested that the polyphenols might have a small influence on its antiviral activity, and other ingredients might have more influence.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] adlay; antiviral effect; cassia seeds; influenza virus; naked barley; soybean
PMID: 28902408 DOI: 10.1002/jsfa.8671