tetano
Editor, Senior Moderator
Viruses. 2017 Aug 12;9(8). pii: E223. doi: 10.3390/v9080223.
[h=1]Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis.[/h] Shim JM[SUP]1[/SUP], Kim J[SUP]2[/SUP], Tenson T[SUP]3[/SUP], Min JY[SUP]4[/SUP], Kainov DE[SUP]5,[/SUP][SUP]6,[/SUP][SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new treatments are urgently needed. Developing new virus control modalities requires better understanding of virus-host interactions. Here, we describe how IAV infection triggers cellular apoptosis and how this process can be exploited towards the development of new therapeutics, which might be more effective than the currently available anti-influenza drugs.
[h=4]KEYWORDS:[/h] antiviral agent; apoptosis; host response; influenza virus; innate immunity
PMID: 28805681 DOI: 10.3390/v9080223
[h=1]Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis.[/h] Shim JM[SUP]1[/SUP], Kim J[SUP]2[/SUP], Tenson T[SUP]3[/SUP], Min JY[SUP]4[/SUP], Kainov DE[SUP]5,[/SUP][SUP]6,[/SUP][SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new treatments are urgently needed. Developing new virus control modalities requires better understanding of virus-host interactions. Here, we describe how IAV infection triggers cellular apoptosis and how this process can be exploited towards the development of new therapeutics, which might be more effective than the currently available anti-influenza drugs.
[h=4]KEYWORDS:[/h] antiviral agent; apoptosis; host response; influenza virus; innate immunity
PMID: 28805681 DOI: 10.3390/v9080223