Influenza Other Respir Viruses . Update on H5N1 Panzootic: Infected Mammal Species Increase by Almost 50% in Just Over a Year

[tetano]

Influenza Other Respir Viruses


. 2025 Sep;19(9):e70159.
doi: 10.1111/irv.70159. Update on H5N1 Panzootic: Infected Mammal Species Increase by Almost 50% in Just Over a Year

Pablo Plaza[SUP] 1 [/SUP], Sergio A Lambertucci[SUP] 1 [/SUP]



Affiliations

• PMID: 40926626
• PMCID: PMC12421138
• DOI: 10.1111/irv.70159

No abstract available Keywords: H5N1; mammals; mixing vessels; panzootic.

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[Commonground]

Excerpts from above report

2.4. Mixing Vessel Species


Almost a quarter of the mammalian species infected (approximately 22%, n = 16) are considered potential mixing vessels (Figure 1A,C) [5]. Seven of them are also domestic or synanthropic (Figure 1A,C). These species should be considered of concern for public health, as they have large populations, live close to humans, and may spread a virus capable of binding to the human α2,6‐linked sialic acid receptor [5]. Health organizations should closely monitor these species of high risk to humans.
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3. Concluding Remarks

The number of mammalian species infected by this zoonotic pathogen and the number of cases are rapidly increasing (Figure 1A,B). Although increased testing may have influenced this result, the almost 50% rise in species in just over a year is highly concerning. Some species pose a significant risk to humans due to their large populations, close proximity to human settlements, and potential role as mixing vessels...

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