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Influenza Other Respir Viruses . The Epidemiology, Phylogeny, and Strain Antigenicity of an Influenza A/H3N2 Virus Outbreak Among Vaccinated US Nav

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses


. 2025 Dec;19(12):e70184.
doi: 10.1111/irv.70184. The Epidemiology, Phylogeny, and Strain Antigenicity of an Influenza A/H3N2 Virus Outbreak Among Vaccinated US Navy Midshipmen

Simon D Pollett[SUP] 1 2 [/SUP], Emily Hone[SUP] 1 2 [/SUP], Stephanie A Richard[SUP] 1 2 [/SUP], Kat Schmidt[SUP] 1 2 [/SUP], Mark P Simons[SUP] 1 [/SUP], Michele Wayman[SUP] 1 2 [/SUP], Jennifer Rothenberg[SUP] 1 2 [/SUP], Vivian Hogan[SUP] 1 2 [/SUP], Robert J O'Connell[SUP] 1 [/SUP], Timothy H Burgess[SUP] 1 [/SUP], Daniel Ewing[SUP] 3 [/SUP], Appavu K Sundaram[SUP] 3 [/SUP], Anthony C Fries[SUP] 4 [/SUP], Drake H Tilley[SUP] 5 [/SUP], Rhonda E Colombo[SUP] 1 2 6 [/SUP]



Affiliations
Free article Abstract

We performed epidemiological, genetic, and antigenic characterization of an influenza A/H3N2 outbreak in a congregate setting of young adults with high vaccination rates. We noted substantial duty-days lost, rapid spread, and vaccine antigenic divergence. The risk of influenza in healthy vaccinated adults underscores the need to develop universal influenza vaccines.

Keywords: US navy; epidemiology; influenza A/H3N2; outbreak; phylogeny; vaccinated.

 
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