Influenza Other Respir Viruses . Risk of symptomatic severe acute respiratory syndrome coronavirus 2 infection not associated with influenza vaccina

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Influenza Other Respir Viruses


. 2021 Jun 25.
doi: 10.1111/irv.12880. Online ahead of print.
Risk of symptomatic severe acute respiratory syndrome coronavirus 2 infection not associated with influenza vaccination in the 2019-2020 season


Jennifer P King[SUP] 1 [/SUP], Huong Q McLean[SUP] 1 [/SUP], Edward A Belongia[SUP] 1 [/SUP]



Affiliations

• PMID: 34169670
• DOI: 10.1111/irv.12880

Abstract

The association of influenza vaccine and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was assessed by test-negative design using data collected for a study of outpatient COVID-19-like illness with onset dates from June to September 2020. Multivariable logistic regression models examined the association between receipt of 2019-2020 influenza vaccine and PCR-confirmed SARS-CoV-2 with adjustment for potential confounders. Receipt of influenza vaccine during the 2019-2020 influenza season was not associated with increased odds of SARS-CoV-2 infection in adults (aOR 0.83, 95% CI 0.63 to 1.10) or children (aOR 0.92, 95% CI 0.47 to 1.80).

Keywords: COVID-19; PCR; SARS-CoV-2; influenza vaccine; outpatient.