tetano
Editor, Senior Moderator
Influenza Other Respir Viruses
. 2021 Jun 10.
doi: 10.1111/irv.12878. Online ahead of print.
Low-pathogenicity influenza viruses replicate differently in laughing gulls and mallards
Miria F Criado[SUP] 1 [/SUP], Kira A Moresco[SUP] 1 [/SUP], David E Stallknecht[SUP] 2 [/SUP], David E Swayne[SUP] 1 [/SUP]
Affiliations
Abstract
Wild aquatic birds are natural reservoirs of low-pathogenicity avian influenza viruses (LPAIVs). Laughing gulls inoculated with four gull-origin LPAIVs (H7N3, H6N4, H3N8, and H2N3) had a predominate respiratory infection. By contrast, mallards inoculated with two mallard-origin LPAIVs (H5N6 and H4N8) became infected and had similar virus titers in oropharyngeal (OP) and cloacal (CL) swabs. The trend toward predominate OP shedding in gulls suggest a greater role of direct bird transmission in maintenance, whereas mallards shedding suggests importance of fecal-oral transmission through water contamination. Additional infectivity and pathogenesis studies are needed to confirm this replication difference for LPAI viruses in gulls.
Keywords: avian influenza; laughing gulls; low-pathogenicity avian influenza; mallard; pathogenesis; pathogenicity; wild birds.
. 2021 Jun 10.
doi: 10.1111/irv.12878. Online ahead of print.
Low-pathogenicity influenza viruses replicate differently in laughing gulls and mallards
Miria F Criado[SUP] 1 [/SUP], Kira A Moresco[SUP] 1 [/SUP], David E Stallknecht[SUP] 2 [/SUP], David E Swayne[SUP] 1 [/SUP]
Affiliations
- PMID: 34109758
- DOI: 10.1111/irv.12878
Abstract
Wild aquatic birds are natural reservoirs of low-pathogenicity avian influenza viruses (LPAIVs). Laughing gulls inoculated with four gull-origin LPAIVs (H7N3, H6N4, H3N8, and H2N3) had a predominate respiratory infection. By contrast, mallards inoculated with two mallard-origin LPAIVs (H5N6 and H4N8) became infected and had similar virus titers in oropharyngeal (OP) and cloacal (CL) swabs. The trend toward predominate OP shedding in gulls suggest a greater role of direct bird transmission in maintenance, whereas mallards shedding suggests importance of fecal-oral transmission through water contamination. Additional infectivity and pathogenesis studies are needed to confirm this replication difference for LPAI viruses in gulls.
Keywords: avian influenza; laughing gulls; low-pathogenicity avian influenza; mallard; pathogenesis; pathogenicity; wild birds.