tetano
Editor, Senior Moderator
Influenza Other Respir Viruses
. 2021 Dec 3.
doi: 10.1111/irv.12933. Online ahead of print.
Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults
Sarah Spencer[SUP] 1 [/SUP], Jessie R Chung[SUP] 1 [/SUP], Edward A Belongia[SUP] 2 [/SUP], Maria Sundaram[SUP] 2 [/SUP], Jennifer Meece[SUP] 2 [/SUP], Laura A Coleman[SUP] 3 2 [/SUP], Richard K Zimmerman[SUP] 4 [/SUP], Mary Patricia Nowalk[SUP] 4 [/SUP], Krissy Moehling Geffel[SUP] 4 [/SUP], Ted Ross[SUP] 5 4 [/SUP], Chalise E Carter[SUP] 5 4 [/SUP], David Shay[SUP] 1 [/SUP], Min Levine[SUP] 1 [/SUP], Justine Liepkalns[SUP] 1 6 [/SUP], Jin Hyang Kim[SUP] 1 7 [/SUP], Suryaprakash Sambhara[SUP] 1 [/SUP], Mark G Thompson[SUP] 1 [/SUP], Brendan Flannery[SUP] 1 [/SUP]
Affiliations
Abstract
Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine in adults aged 50-80 with and without type 2 diabetes mellitus. Serologic response to influenza vaccination was similar in both groups: greater fold-increases in antibody titer occurred among participants with lower pre-vaccination antibody titers. Waning of antibody titers was not influenced by diabetes status.
Keywords: influenza; serologic response; vaccine.
. 2021 Dec 3.
doi: 10.1111/irv.12933. Online ahead of print.
Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults
Sarah Spencer[SUP] 1 [/SUP], Jessie R Chung[SUP] 1 [/SUP], Edward A Belongia[SUP] 2 [/SUP], Maria Sundaram[SUP] 2 [/SUP], Jennifer Meece[SUP] 2 [/SUP], Laura A Coleman[SUP] 3 2 [/SUP], Richard K Zimmerman[SUP] 4 [/SUP], Mary Patricia Nowalk[SUP] 4 [/SUP], Krissy Moehling Geffel[SUP] 4 [/SUP], Ted Ross[SUP] 5 4 [/SUP], Chalise E Carter[SUP] 5 4 [/SUP], David Shay[SUP] 1 [/SUP], Min Levine[SUP] 1 [/SUP], Justine Liepkalns[SUP] 1 6 [/SUP], Jin Hyang Kim[SUP] 1 7 [/SUP], Suryaprakash Sambhara[SUP] 1 [/SUP], Mark G Thompson[SUP] 1 [/SUP], Brendan Flannery[SUP] 1 [/SUP]
Affiliations
- PMID: 34859584
- DOI: 10.1111/irv.12933
Abstract
Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine in adults aged 50-80 with and without type 2 diabetes mellitus. Serologic response to influenza vaccination was similar in both groups: greater fold-increases in antibody titer occurred among participants with lower pre-vaccination antibody titers. Waning of antibody titers was not influenced by diabetes status.
Keywords: influenza; serologic response; vaccine.