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Influenza in Yucatan in 2018: Chronology, characteristics and outcomes of ambulatory and hospitalized patients

tetano

Editor, Senior Moderator
Braz J Infect Dis. 2019 Sep 24. pii: S1413-8670(19)30427-1. doi: 10.1016/j.bjid.2019.08.009. [Epub ahead of print] [h=1]Influenza in Yucatan in 2018: Chronology, characteristics and outcomes of ambulatory and hospitalized patients.[/h]
Mendez-Dominguez NI[SUP]1[/SUP], Bobadilla-Rosado LO[SUP]2[/SUP], Fajardo-Ruiz LS[SUP]3[/SUP], Camara-Salazar A[SUP]4[/SUP], Gomez-Carro S[SUP]5[/SUP].
[h=3]Author information[/h] 1 Universidad Marista de M?rida, Escuela de Medicina, School of Medicine, Perif?rico Norte Tablaje Catastral 13941 Carretera M?rida - Progreso, C.P. 97300, M?rida, Yucat?n, Mexico. Electronic address: ninamendezdominguez@gmail.com. 2 Universidad Marista de M?rida, Escuela de Medicina, School of Medicine, Perif?rico Norte Tablaje Catastral 13941 Carretera M?rida - Progreso, C.P. 97300, M?rida, Yucat?n, Mexico. Electronic address: o.r.luis@hotmail.com. 3 Universidad Marista de M?rida, Escuela de Medicina, School of Medicine, Perif?rico Norte Tablaje Catastral 13941 Carretera M?rida - Progreso, C.P. 97300, M?rida, Yucat?n, Mexico. Electronic address: sabrinafajardoruiz@gmail.com. 4 Universidad Marista de M?rida, Escuela de Medicina, School of Medicine, Perif?rico Norte Tablaje Catastral 13941 Carretera M?rida - Progreso, C.P. 97300, M?rida, Yucat?n, Mexico. Electronic address: andrea.camarasalazar@gmail.com. 5 O?Horan General Hospital, Departmento de Epidemiologia, Avenida Itz?es x avenida Jacinto Canek, CP. 97000, M?rida, Yucat?n, Mexico. Electronic address: salvador.gomez@ssy.gob.mx.

[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Influenza season is expected between October and February in the northern hemisphere, including Mexico. Previous studies suggested that transmission peak may occur earlier in Yucatan, a state in southeast Mexico.
[h=4]OBJECTIVES:[/h] (a) Describe the seasonality of 2018 influenza cases seen at O?Horan hospital, statewide, and nationwide; (b) analyze the characteristics, clinical manifestations and outcomes of ambulatory and hospitalized patients; (c) analyze fatal outcomes occurrence among vaccinated and unvaccinated individuals.
[h=4]METHODS:[/h] Retrospective analytic cohort of all confirmed influenza cases assisted at O?Horan hospital during 2018, along with a chronologic graphic description of the statewide epidemic curve from the epidemiological surveillance registries.
[h=4]RESULTS:[/h] A total of 264 influenza cases were analyzed; 145 (55%) were female; 26% were vaccinated. Health workers and unvaccinated individuals were more prone to develop severe cases. Dyspnea and tachypnea were strong predictors of hospitalization; headache, myalgias, arthralgias and rhinorrhea correlated inversely. 236 (89.47%) cases occurred in July and 22 of the 23 deaths occurred before October. No fatal outcomes were observed among vaccinated individuals. Influenza AH1N1 represented 83.6% of serotyped cases.
[h=4]DISCUSSION:[/h] Onset of influenza season in Yucatan may reflect a need for rethinking timing of vaccination and of preventive campaigns, as most cases occurred before vaccination period.
Copyright ? 2019 Sociedade Brasileira de Infectologia. Published by Elsevier Espa?a, S.L.U. All rights reserved.


[h=4]KEYWORDS:[/h] Hospitalization; Infection; Influenza virus; Signs and symptoms

PMID: 31560880 DOI: 10.1016/j.bjid.2019.08.009
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