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Influenza illness averted by influenza vaccination among school year children in Beijing, 2013-2016

tetano

Editor, Senior Moderator
Influenza Other Respir Viruses. 2018 Jun 14. doi: 10.1111/irv.12585. [Epub ahead of print]
[h=1]Influenza illness averted by influenza vaccination among school year children in Beijing, 2013-2016.[/h] Zhang Y[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Cao Z[SUP]4[/SUP], Costantino V[SUP]3[/SUP], Muscatello DJ[SUP]3[/SUP], Chughtai AA[SUP]3[/SUP], Yang P[SUP]1,[/SUP][SUP]2[/SUP], Wang Q[SUP]1,[/SUP][SUP]2[/SUP], MacIntyre CR[SUP]3,[/SUP][SUP]5[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The benefit of school-based influenza vaccination policy has not been fully addressed in Beijing.
[h=4]OBJECTIVES:[/h] To evaluate the benefit of school-based influenza vaccination policy launched in Beijing.
[h=4]METHODS:[/h] Using existing surveillance and immunization data, we developed a dynamic transmission model to assess the impact of influenza vaccination in school-going children. The outcome was defined as the averted number of medically attended influenza illnesses and the prevented disease fraction to all children aged 5-14 years for the 2013/14, 2014/15, and 2015/16 seasons.
[h=4]RESULTS:[/h] We estimated that during the three consecutive influenza seasons, the averted number of medically attended influenza illnesses among children aged 5-14 years was around 104,000 (95% CI: 101,000-106,000), 23,000 (95% CI: 22,000-23,000), and 21,000 (95% CI: 21,000-22,000), respectively. Corresponding prevented fractions to all children aged 5-14 years were 76.3%, 38.5%, and 43.9%.
[h=4]CONCLUSIONS:[/h] In Beijing, school-based vaccinations reduced a substantial number of medically attended influenza illnesses despite seasonal variation in the prevented fraction. This is strong supportive evidence for the continuation of school-based vaccination programs to reduce the influenza burden in this age group. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] Influenza; Models; Students; Vaccination

PMID: 29905021 DOI: 10.1111/irv.12585
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