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Influenza B false-positive results by rapid molecular tests Alere? i Influenza A&B 2 in France

tetano

Editor, Senior Moderator
Diagn Microbiol Infect Dis. 2019 Mar 13. pii: S0732-8893(19)30094-X. doi: 10.1016/j.diagmicrobio.2019.03.002. [Epub ahead of print]
[h=1]Influenza B false-positive results by rapid molecular tests Alere? i Influenza A&B 2 in France.[/h] Otto MP[SUP]1[/SUP], Toyer AL[SUP]2[/SUP], Poggi C[SUP]2[/SUP], Janvier F[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] The Alere-i? Influenza A&B (Abbott), a nicking endonuclease amplification reaction test, has recently been improved in order to deliver results in a few minutes. Our field observation highlights two problems with this new version: improper interpretation of a test as valid despite improper reagent hydration and falsely influenza B positive results. We advise users of the new system to check reagent hydration prior to reporting a result and to systematically confirm positive influenza B results.
Copyright ? 2019 Elsevier Inc. All rights reserved.


[h=4]KEYWORDS:[/h] Alere i a/B 2; False positive; Influenza; Rapid molecular tests

PMID: 30971360 DOI: 10.1016/j.diagmicrobio.2019.03.002
 
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