tetano
Editor, Senior Moderator
Microb Pathog. 2012 Dec 12. pii: S0882-4010(12)00205-7. doi: 10.1016/j.micpath.2012.11.013. [Epub ahead of print]
Influenza and respiratory syncytial virus (RSV) vaccines for infants: safety, immunogenicity, and efficacy.
Beeler JA, Eichelberger MC.
Source
Division of Viral Products, CBER, OVRR, FDA. Electronic address: judy.beeler@fda.hhs.gov.
Abstract
Respiratory viral infections in infants and young children frequently cause illness that can easily progress to hospitalization and death. There are currently no licensed vaccines to prevent respiratory viral disease in children younger than 6 months, reflecting safety concerns and the difficulty in inducing effective immune responses in infants. This review discusses vaccines that have been developed, or are currently being developed, against influenza and respiratory syncytial virus, with a focus on studies performed to demonstrate their safety and efficacy, and the impact of immunologic immaturity and maternal antibodies on the infant response to vaccines.
Copyright ? 2012. Published by Elsevier Ltd.
PMID:
23247146
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23247146
Influenza and respiratory syncytial virus (RSV) vaccines for infants: safety, immunogenicity, and efficacy.
Beeler JA, Eichelberger MC.
Source
Division of Viral Products, CBER, OVRR, FDA. Electronic address: judy.beeler@fda.hhs.gov.
Abstract
Respiratory viral infections in infants and young children frequently cause illness that can easily progress to hospitalization and death. There are currently no licensed vaccines to prevent respiratory viral disease in children younger than 6 months, reflecting safety concerns and the difficulty in inducing effective immune responses in infants. This review discusses vaccines that have been developed, or are currently being developed, against influenza and respiratory syncytial virus, with a focus on studies performed to demonstrate their safety and efficacy, and the impact of immunologic immaturity and maternal antibodies on the infant response to vaccines.
Copyright ? 2012. Published by Elsevier Ltd.
PMID:
23247146
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23247146