tetano
Editor, Senior Moderator
Infect Genet Evol. 2011 May 11. [Epub ahead of print]
Influenza A/H1N1pdm virus in Russian Asia in 2009-2010.
Ilyicheva T, Susloparov I, Durymanov A, Romanovskaya A, Sharshov K, Kurskaya O, Ignashkina M, Shestopalov A.
Source
State Research Center of Virology and Biotechnology "Vector", Koltsovo, Novosibirsk Region, 630559, Russia; Novosibirsk State University, Pirogov St., 2, Novosibirsk, 630090, Russia.
Abstract
In total 3566 blood sera samples were collected in the Russian Far East and Central and Western Siberia in 2009-2010. The presence of antibodies to influenza A/H1N1pdm, seasonal H1N1 and H3N2 influenza viruses in the sera was tested in the hemagglutination inhibition test. 29.5% of samples from the Far East were positive to pandemic influenza, this value for Central and Western Siberia is 2-fold lower (12.8% and 11%, respectively). Fifty-six influenza A/H1N1pdm viruses were isolated during 2009-2010 from samples collected in Central and Western Siberia and the Russian Far East. Molecular and genetic properties of 23 strains were studied. Nucleotide and amino-acid sequences of pandemic influenza virus strains were identical (99% identity or more) to reference strain A/California/04/2009. Sporadic substitutions in antigenic sites were detected but did not change antigenic characteristics of strains.
Copyright ? 2011. Published by Elsevier B.V.
PMID:
21600305
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21600305
Influenza A/H1N1pdm virus in Russian Asia in 2009-2010.
Ilyicheva T, Susloparov I, Durymanov A, Romanovskaya A, Sharshov K, Kurskaya O, Ignashkina M, Shestopalov A.
Source
State Research Center of Virology and Biotechnology "Vector", Koltsovo, Novosibirsk Region, 630559, Russia; Novosibirsk State University, Pirogov St., 2, Novosibirsk, 630090, Russia.
Abstract
In total 3566 blood sera samples were collected in the Russian Far East and Central and Western Siberia in 2009-2010. The presence of antibodies to influenza A/H1N1pdm, seasonal H1N1 and H3N2 influenza viruses in the sera was tested in the hemagglutination inhibition test. 29.5% of samples from the Far East were positive to pandemic influenza, this value for Central and Western Siberia is 2-fold lower (12.8% and 11%, respectively). Fifty-six influenza A/H1N1pdm viruses were isolated during 2009-2010 from samples collected in Central and Western Siberia and the Russian Far East. Molecular and genetic properties of 23 strains were studied. Nucleotide and amino-acid sequences of pandemic influenza virus strains were identical (99% identity or more) to reference strain A/California/04/2009. Sporadic substitutions in antigenic sites were detected but did not change antigenic characteristics of strains.
Copyright ? 2011. Published by Elsevier B.V.
PMID:
21600305
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/21600305