tetano
Editor, Senior Moderator
Interdiscip Perspect Infect Dis. 2014;2014:470825. doi: 10.1155/2014/470825. Epub 2014 Oct 14.
Influenza A/H1N1 Severe Pneumonia: Novel Morphocytological Findings in Bronchoalveolar Lavage.
Faverio P1, Aliberti S2, Ezekiel C3, Messinesi G2, Brenna A4, Pesci A2.
Author information
Abstract
We present the results of bronchoalveolar lavage (BAL) performed in three patients with severe influenza A/H1N1 pneumonia complicated by acute respiratory distress syndrome (ARDS). Light microscopy analysis of BAL cytocentrifugates showed the presence of characteristic large, mononuclear, plasmoblastic/plasmocytoid-like cells never described before. Via transmission electron microscopy, these cells were classified as atypical type II pneumocytes and some of them showed cytoplasmic vesicles and inclusions. We concluded that plasmoblastic/plasmocytoid-like type II pneumocytes might represent a morphologic marker of A/H1N1 influenza virus infection as well as reparative cellular activation after diffuse alveolar damage.
PMID:
25383078
[PubMed]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/25383078
Influenza A/H1N1 Severe Pneumonia: Novel Morphocytological Findings in Bronchoalveolar Lavage.
Faverio P1, Aliberti S2, Ezekiel C3, Messinesi G2, Brenna A4, Pesci A2.
Author information
Abstract
We present the results of bronchoalveolar lavage (BAL) performed in three patients with severe influenza A/H1N1 pneumonia complicated by acute respiratory distress syndrome (ARDS). Light microscopy analysis of BAL cytocentrifugates showed the presence of characteristic large, mononuclear, plasmoblastic/plasmocytoid-like cells never described before. Via transmission electron microscopy, these cells were classified as atypical type II pneumocytes and some of them showed cytoplasmic vesicles and inclusions. We concluded that plasmoblastic/plasmocytoid-like type II pneumocytes might represent a morphologic marker of A/H1N1 influenza virus infection as well as reparative cellular activation after diffuse alveolar damage.
PMID:
25383078
[PubMed]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/25383078