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Influenza A H1N1 infection in pregnant patients

tetano

Editor, Senior Moderator
Rev Med Inst Mex Seguro Soc. 2010 July-August;48(4):399-404.
[Influenza A H1N1 infection in pregnant patients.]

[Article in Spanish]

Bello-Carrera R, Romero-L?pez Z, Ochoa-V?zquez MD, Reyes-Calder?n H, Rico-M?ndez FG.

Departamento de Neumolog?a, Hospital General, Centro M?dico Nacional La Raza, Instituto Mexicano del Seguro Social, Distrito Federal, M?xico. vyky0110@hotmail.com.mx.
Abstract

Background: despite the severity of infection with influenza virus, little has been reported about its presence in pregnant women. Objective: to communicate our experience on influenza virus H1N1 in pregnant women. Methods: we conducted a retrospective cohort study on 16 hospitalized patients with diagnosis of pregnancy and probable or confirmed case of infection with H1N1 influenza virus. Suspected case: sudden onset of respiratory infectious process, in 2009, in Mexico City. All cases underwent the fast detection test and subsequently confirmation by PCR test. Discharge criteria: clinical improvement, PaO(2) above 60 mm Hg and absence of bilateral consolidation on chest radiographs. Severity criteria: type I respiratory failure (PaO(2) < 50 mm Hg) who required mechanical ventilatory support, radiographic pattern compatible with multisegmental pneumonia and PaO(2)/FiO(2) < 200 mm Hg. Results: the pregnant patient mortality was 4.25%. The average age was 25.8 years, with 24.13 weeks of gestation with 5.6 days average of hospital stay. The main co-morbidity was obesity. Conclusions: the fatal cases were those with longer time of evolution and late diagnosis.

PMID: 21194509 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/21194509
 
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