tetano
Editor, Senior Moderator
Eur J Clin Microbiol Infect Dis. 2016 Mar 15. [Epub ahead of print]
[h=1]Influenza A and B co-infection: a case-control study and review of the literature.[/h] P?rez-Garc?a F[SUP]1[/SUP], V?squez V[SUP]2[/SUP], de Egea V[SUP]2,[/SUP][SUP]3[/SUP], Catal?n P[SUP]2[/SUP], Rodr?guez-S?nchez B[SUP]2,[/SUP][SUP]3[/SUP], Bouza E[SUP]4,[/SUP][SUP]5,[/SUP][SUP]6,[/SUP][SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza virus infection remains a major cause of morbidity and mortality during winter seasons. Bacterial and virus co-infection is a commonly described situation in these patients. However, data on co-infection by influenza A and B viruses are lacking. In this study, we present the cases of co-infection by influenza A and B viruses during the winter season of 2014-2015 in our institution. We analyzed 2759 samples from 2111 patients and found that 625 samples corresponding to 609 patients were positive for influenza A or B virus. A total of 371 patients had influenza A, 228 had influenza B, and 10 (1.6 %) had influenza A and B virus detection in the same sample. The median age of co-infected patients was 78.6 years, and only one of the co-infected patients died because of the infection. Comparison with a control group of mono-infected patients revealed that co-infection was significantly associated with nosocomial acquisition [odds ratio (OR) = 4.5, 95 % confidence interval (CI) = 1.05-19.25, p = 0.042]. However, co-infection was not associated with worse outcome, previous underlying condition, or vaccination status. Multivariate analysis revealed that co-infection was not an independent risk factor for death and that no single risk factor could predict co-infection.
PMID: 26980094 [PubMed - as supplied by publisher]
[h=1]Influenza A and B co-infection: a case-control study and review of the literature.[/h] P?rez-Garc?a F[SUP]1[/SUP], V?squez V[SUP]2[/SUP], de Egea V[SUP]2,[/SUP][SUP]3[/SUP], Catal?n P[SUP]2[/SUP], Rodr?guez-S?nchez B[SUP]2,[/SUP][SUP]3[/SUP], Bouza E[SUP]4,[/SUP][SUP]5,[/SUP][SUP]6,[/SUP][SUP]7[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza virus infection remains a major cause of morbidity and mortality during winter seasons. Bacterial and virus co-infection is a commonly described situation in these patients. However, data on co-infection by influenza A and B viruses are lacking. In this study, we present the cases of co-infection by influenza A and B viruses during the winter season of 2014-2015 in our institution. We analyzed 2759 samples from 2111 patients and found that 625 samples corresponding to 609 patients were positive for influenza A or B virus. A total of 371 patients had influenza A, 228 had influenza B, and 10 (1.6 %) had influenza A and B virus detection in the same sample. The median age of co-infected patients was 78.6 years, and only one of the co-infected patients died because of the infection. Comparison with a control group of mono-infected patients revealed that co-infection was significantly associated with nosocomial acquisition [odds ratio (OR) = 4.5, 95 % confidence interval (CI) = 1.05-19.25, p = 0.042]. However, co-infection was not associated with worse outcome, previous underlying condition, or vaccination status. Multivariate analysis revealed that co-infection was not an independent risk factor for death and that no single risk factor could predict co-infection.
PMID: 26980094 [PubMed - as supplied by publisher]