tetano
Editor, Senior Moderator
Infect Prev Pract
. 2022 Dec 30;100267.
doi: 10.1016/j.infpip.2022.100267. Online ahead of print.
Risk of SARS-CoV-2 infection in healthcare workers with inflammatory bowel disease: a case-control study
Aurelien Amiot[SUP] 1 [/SUP], Anne Bourrier[SUP] 2 [/SUP], Jean-Marc Gornet[SUP] 3 [/SUP], Olivier Dewit[SUP] 4 [/SUP], Stephane Nancey[SUP] 5 [/SUP], Romain Altwegg[SUP] 6 [/SUP], Vered Abitbol[SUP] 7 [/SUP], David Laharie[SUP] 8 [/SUP], Catherine Reenaers[SUP] 9 [/SUP], Charlotte Gagnière[SUP] 10 [/SUP], Anthony Buisson[SUP] 11 [/SUP], Maria Nachury[SUP] 12 [/SUP], Stephanie Viennot[SUP] 13 [/SUP], Lucine Vuitton[SUP] 14 [/SUP], Carmen Stefanescu[SUP] 15 [/SUP], Philippe Marteau[SUP] 16 [/SUP], Guillaume Bouguen[SUP] 17 [/SUP], Philippe Seksik[SUP] 2 [/SUP]; GETAID-INFOPRO study group
Affiliations
Abstract
Background: Whether healthcare workers with inflammatory bowel disease (IBD) are at increased risk of Novel coronavirus disease (COVID-19) due to occupational exposure is unknown.
Aim: To assess the risk of COVID-19 in healthcare workers with IBD.
Methods: A case control study enrolled 326 healthcare workers with IBD from 17 GETAID centres and matched non-healthcare workers with IBD controls (1:1) for gender, age, disease subtype and year of diagnosis. The study period was year 2020 during the COVID-19 outbreak.
Results: In total, 59 COVID-19 were recorded among cases (n = 32) and controls (n = 27), including 2 severe COVID-19 (requiring hospitalization, mechanic ventilation) but no death. No difference was observed between healthcare workers and controls regarding the overall incidence rates of COVID-19 4.9 ± 2.2 vs. 3.8 ± 1.9 per 100 patient-semesters, P = 0.34) and the overall incidence rates of severe COVID-19 (0.6 ± 7.8 vs. 0.3 ± 5.5 per 100 patient-semesters, P = 0.42). In multivariate analysis in the entire study population, COVID-19 was associated with patients with body mass index > 30 kg/m[SUP]2[/SUP] (HR = 2.48, 95%CI [1.13-5.44], P = 0.02).
Conclusion: Healthcare workers with IBD do not have an increased risk of COVID-19 compared with other patients with IBD.
Keywords: COVID-19, Novel coronavirus disease; CRP, C-reactive protein; Crohn's disease; Healthcare worker; IBD, inflammatory bowel disease; Inflammatory bowel disease; SARS-CoV-2; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TNF, tumor necrosis factor-alpha; UC, ulcerative colitis; Ulcerative colitis.
. 2022 Dec 30;100267.
doi: 10.1016/j.infpip.2022.100267. Online ahead of print.
Risk of SARS-CoV-2 infection in healthcare workers with inflammatory bowel disease: a case-control study
Aurelien Amiot[SUP] 1 [/SUP], Anne Bourrier[SUP] 2 [/SUP], Jean-Marc Gornet[SUP] 3 [/SUP], Olivier Dewit[SUP] 4 [/SUP], Stephane Nancey[SUP] 5 [/SUP], Romain Altwegg[SUP] 6 [/SUP], Vered Abitbol[SUP] 7 [/SUP], David Laharie[SUP] 8 [/SUP], Catherine Reenaers[SUP] 9 [/SUP], Charlotte Gagnière[SUP] 10 [/SUP], Anthony Buisson[SUP] 11 [/SUP], Maria Nachury[SUP] 12 [/SUP], Stephanie Viennot[SUP] 13 [/SUP], Lucine Vuitton[SUP] 14 [/SUP], Carmen Stefanescu[SUP] 15 [/SUP], Philippe Marteau[SUP] 16 [/SUP], Guillaume Bouguen[SUP] 17 [/SUP], Philippe Seksik[SUP] 2 [/SUP]; GETAID-INFOPRO study group
Affiliations
- PMID: 36601289
- PMCID: PMC9800326
- DOI: 10.1016/j.infpip.2022.100267
Abstract
Background: Whether healthcare workers with inflammatory bowel disease (IBD) are at increased risk of Novel coronavirus disease (COVID-19) due to occupational exposure is unknown.
Aim: To assess the risk of COVID-19 in healthcare workers with IBD.
Methods: A case control study enrolled 326 healthcare workers with IBD from 17 GETAID centres and matched non-healthcare workers with IBD controls (1:1) for gender, age, disease subtype and year of diagnosis. The study period was year 2020 during the COVID-19 outbreak.
Results: In total, 59 COVID-19 were recorded among cases (n = 32) and controls (n = 27), including 2 severe COVID-19 (requiring hospitalization, mechanic ventilation) but no death. No difference was observed between healthcare workers and controls regarding the overall incidence rates of COVID-19 4.9 ± 2.2 vs. 3.8 ± 1.9 per 100 patient-semesters, P = 0.34) and the overall incidence rates of severe COVID-19 (0.6 ± 7.8 vs. 0.3 ± 5.5 per 100 patient-semesters, P = 0.42). In multivariate analysis in the entire study population, COVID-19 was associated with patients with body mass index > 30 kg/m[SUP]2[/SUP] (HR = 2.48, 95%CI [1.13-5.44], P = 0.02).
Conclusion: Healthcare workers with IBD do not have an increased risk of COVID-19 compared with other patients with IBD.
Keywords: COVID-19, Novel coronavirus disease; CRP, C-reactive protein; Crohn's disease; Healthcare worker; IBD, inflammatory bowel disease; Inflammatory bowel disease; SARS-CoV-2; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; TNF, tumor necrosis factor-alpha; UC, ulcerative colitis; Ulcerative colitis.