tetano
Editor, Senior Moderator
Infect Drug Resist
. 2020 Jul 31;13:2637-2640.
doi: 10.2147/IDR.S259984. eCollection 2020.
Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
Zhenguo Wang[SUP] #[/SUP][SUP] 1 [/SUP], Xiaojun Hu[SUP] #[/SUP][SUP] 2 [/SUP], Zhonghe Li[SUP] #[/SUP][SUP] 3 [/SUP], Changli Tu[SUP] 1 [/SUP], Yiming Wang[SUP] 4 [/SUP], Pengfei Pang[SUP] 2 [/SUP], Huitao Zhang[SUP] #[/SUP][SUP] 2 [/SUP], Xiaobin Zheng[SUP] 1 [/SUP], Yingjian Liang[SUP] 1 [/SUP], Hong Shan[SUP] 2 [/SUP], Jing Liu[SUP] 1 [/SUP]
Affiliations
Abstract
Methods: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway.
Results: In these nasopharyngeal test paper samples, 38 kinds of bacteria, 10 kinds of viruses except SARS-CoV-2, nine kinds of fungi and three kinds of atypical pathogens had been found. There was some difference in microbial composition in the upper airway between severe and non-severe cases.
Summary: These results are important for us to study the effect of SARS-CoV-2 on the local microbial composition of upper airway and prevent opportunistic infection in severe patients.
Keywords: SARS-CoV-2; microbial composition; next generation sequencing; NGS; upper airway.
. 2020 Jul 31;13:2637-2640.
doi: 10.2147/IDR.S259984. eCollection 2020.
Effect of SARS-CoV-2 Infection on the Microbial Composition of Upper Airway
Zhenguo Wang[SUP] #[/SUP][SUP] 1 [/SUP], Xiaojun Hu[SUP] #[/SUP][SUP] 2 [/SUP], Zhonghe Li[SUP] #[/SUP][SUP] 3 [/SUP], Changli Tu[SUP] 1 [/SUP], Yiming Wang[SUP] 4 [/SUP], Pengfei Pang[SUP] 2 [/SUP], Huitao Zhang[SUP] #[/SUP][SUP] 2 [/SUP], Xiaobin Zheng[SUP] 1 [/SUP], Yingjian Liang[SUP] 1 [/SUP], Hong Shan[SUP] 2 [/SUP], Jing Liu[SUP] 1 [/SUP]
Affiliations
- PMID: 32801801
- PMCID: PMC7406177
- DOI: 10.2147/IDR.S259984
Abstract
Methods: Forty-four COVID-19 patients (severe/critical: N = 8, non-severe: N = 36) were examined by next generation sequencing (NGS) of nasopharyngeal test paper to observe the effect of novel coronavirus infection to the microbial composition in upper airway.
Results: In these nasopharyngeal test paper samples, 38 kinds of bacteria, 10 kinds of viruses except SARS-CoV-2, nine kinds of fungi and three kinds of atypical pathogens had been found. There was some difference in microbial composition in the upper airway between severe and non-severe cases.
Summary: These results are important for us to study the effect of SARS-CoV-2 on the local microbial composition of upper airway and prevent opportunistic infection in severe patients.
Keywords: SARS-CoV-2; microbial composition; next generation sequencing; NGS; upper airway.