tetano
Editor, Senior Moderator
Infect Control Hosp Epidemiol
. 2022 Aug 31;1-8.
doi: 10.1017/ice.2022.203. Online ahead of print.
Characterizing the relationship between coronavirus disease 2019 (COVID-19) and central-line-associated bloodstream infection (CLABSI) and assessing the impact of a nursing-focused CLABSI reduction intervention during the COVID-19 pandemic
Michael A Ben-Aderet[SUP] 1 [/SUP], Meghan S Madhusudhan[SUP] 1 [/SUP], Pishoy Haroun[SUP] 2 [/SUP], Matthew J P Almario[SUP] 1 [/SUP], Ryan Raypon[SUP] 1 [/SUP], Sharon Fawcett[SUP] 1 [/SUP], Julie Johnson[SUP] 1 [/SUP], Anita Girard[SUP] 3 [/SUP], Todd Griner[SUP] 3 [/SUP], Lorraine Sheffield[SUP] 3 [/SUP], Jonathan D Grein[SUP] 1 [/SUP]
Affiliations
Abstract
Objective: To examine the impact of SARS-CoV-2 infection on CLABSI rate and characterize the patients who developed a CLABSI. We also examined the impact of a CLABSI-reduction quality-improvement project in patients with and without COVID-19.
Design: Retrospective cohort analysis.
Setting: Academic 889-bed tertiary-care teaching hospital in urban Los Angeles.
Patients or participants: Inpatients 18 years and older with CLABSI as defined by the National Healthcare Safety Network (NHSN).
Intervention(s): CLABSI rate and patient characteristics were analyzed for 2 cohorts during the pandemic era (March 2020-August 2021): COVID-19 CLABSI patients and non-COVID-19 CLABSI patients, based on diagnosis of COVID-19 during admission. Secondary analyses were non-COVID-19 CLABSI rate versus a historical control period (2019), ICU CLABSI rate in COVID-19 versus non-COVID-19 patients, and CLABSI rates before and after a quality- improvement initiative.
Results: The rate of COVID-19 CLABSI was significantly higher than non-COVID-19 CLABSI. We did not detect a difference between the non-COVID-19 CLABSI rate and the historical control. COVID-19 CLABSIs occurred predominantly in the ICU, and the ICU COVID-19 CLABSI rate was significantly higher than the ICU non-COVID-19 CLABSI rate. A hospital-wide quality-improvement initiative reduced the rate of non-COVID-19 CLABSI but not COVID-19 CLABSI.
Conclusions: Patients hospitalized for COVID-19 have a significantly higher CLABSI rate, particularly in the ICU setting. Reasons for this increase are likely multifactorial, including both patient-specific and process-related issues. Focused quality-improvement efforts were effective in reducing CLABSI rates in non-COVID-19 patients but were less effective in COVID-19 patients.
. 2022 Aug 31;1-8.
doi: 10.1017/ice.2022.203. Online ahead of print.
Characterizing the relationship between coronavirus disease 2019 (COVID-19) and central-line-associated bloodstream infection (CLABSI) and assessing the impact of a nursing-focused CLABSI reduction intervention during the COVID-19 pandemic
Michael A Ben-Aderet[SUP] 1 [/SUP], Meghan S Madhusudhan[SUP] 1 [/SUP], Pishoy Haroun[SUP] 2 [/SUP], Matthew J P Almario[SUP] 1 [/SUP], Ryan Raypon[SUP] 1 [/SUP], Sharon Fawcett[SUP] 1 [/SUP], Julie Johnson[SUP] 1 [/SUP], Anita Girard[SUP] 3 [/SUP], Todd Griner[SUP] 3 [/SUP], Lorraine Sheffield[SUP] 3 [/SUP], Jonathan D Grein[SUP] 1 [/SUP]
Affiliations
- PMID: 36043349
- DOI: 10.1017/ice.2022.203
Abstract
Objective: To examine the impact of SARS-CoV-2 infection on CLABSI rate and characterize the patients who developed a CLABSI. We also examined the impact of a CLABSI-reduction quality-improvement project in patients with and without COVID-19.
Design: Retrospective cohort analysis.
Setting: Academic 889-bed tertiary-care teaching hospital in urban Los Angeles.
Patients or participants: Inpatients 18 years and older with CLABSI as defined by the National Healthcare Safety Network (NHSN).
Intervention(s): CLABSI rate and patient characteristics were analyzed for 2 cohorts during the pandemic era (March 2020-August 2021): COVID-19 CLABSI patients and non-COVID-19 CLABSI patients, based on diagnosis of COVID-19 during admission. Secondary analyses were non-COVID-19 CLABSI rate versus a historical control period (2019), ICU CLABSI rate in COVID-19 versus non-COVID-19 patients, and CLABSI rates before and after a quality- improvement initiative.
Results: The rate of COVID-19 CLABSI was significantly higher than non-COVID-19 CLABSI. We did not detect a difference between the non-COVID-19 CLABSI rate and the historical control. COVID-19 CLABSIs occurred predominantly in the ICU, and the ICU COVID-19 CLABSI rate was significantly higher than the ICU non-COVID-19 CLABSI rate. A hospital-wide quality-improvement initiative reduced the rate of non-COVID-19 CLABSI but not COVID-19 CLABSI.
Conclusions: Patients hospitalized for COVID-19 have a significantly higher CLABSI rate, particularly in the ICU setting. Reasons for this increase are likely multifactorial, including both patient-specific and process-related issues. Focused quality-improvement efforts were effective in reducing CLABSI rates in non-COVID-19 patients but were less effective in COVID-19 patients.